Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | GRM5 | P41594 | 1/20 | 0.43 |
| ▸ | RORC | P51449 | 3/20 | 0.43 |
| ▸ | DHODH | Q02127 | 2/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.41 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | RXRB | P28702 | 1/20 | 0.41 |
| ▸ | RXRG | P48443 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9965406 | 0.88 | TRPV1 (0.51) | TDP1TP53GAAMAPTPOLB | |
| SCHEMBL9965458 | 0.83 | TP53 (0.49) | TDP1TP53GAAMAPTPOLB | |
| SCHEMBL9965408 | 0.79 | GAA (0.49) | TDP1GAAPTPN1POLBMEN1 | |
| SCHEMBL14639571 | 0.79 | TSHR (0.42) | MAPTMEN1KMT2AL3MBTL1 | |
| SCHEMBL10173892 | 0.73 | GAA (0.54) | GAAPTPN1POLBMEN1KMT2A | |
| SCHEMBL9965459 | 0.73 | GAA (0.53) | TDP1GAAPTPN1POLBMEN1 | |
| SCHEMBL9965441 | 0.70 | SMN1; SMN2 (0.48) | GAAMAPTPTPN1POLBGRM5 | |
| SCHEMBL9965398 | 0.69 | SMN1; SMN2 (0.50) | TDP1GAAMAPTPTPN1GRM5 | |
| SCHEMBL8300495 | 0.68 | KMT2A (0.65) | GAAPOLBTHRBKMT2A | |
| SCHEMBL14639717 | 0.68 | GAA (0.49) | TP53GAAMAPTPOLBTRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007003934-A2 | 17BETA-HYDR0XYSTER0ID DEHYDROGENASE TYPE 3 (17BETA-HSD3 ) INHIBITORS | STERIX LIMITED (GB) | 2007-01-11 | — | — | WO | disclosed |