Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 2/20 | 0.49 |
| ▸ | BCR | P11274 | 2/20 | 0.49 |
| ▸ | SMYD3 | Q9H7B4 | 5/20 | 0.47 |
| ▸ | NPC1 | O15118 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.45 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.45 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.45 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.45 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.43 |
| ▸ | BMPR1A | P36894 | 1/20 | 0.43 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.43 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.43 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.43 |
| ▸ | HPGDS | O60760 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14640449 | 0.89 | KMT2A (0.53) | ABL1BCRSMYD3NPC1KMT2A | |
| SCHEMBL17470865 | 0.82 | TRPV1 (0.60) | NPC1KMT2ARAB9AMEN1SMN1; SMN2 | |
| SCHEMBL14640427 | 0.80 | TSHR (0.53) | NPC1KMT2ARAB9AMEN1 | |
| SCHEMBL5606272 | 0.80 | MEN1 (0.74) | KMT2AMEN1SMN1; SMN2LMNA | |
| SCHEMBL28125494 | 0.79 | XDH (0.61) | ABL1BCRSMYD3NPC1KMT2A | |
| SCHEMBL17806746 | 0.79 | MKNK1 (0.52) | — | |
| SCHEMBL517808 | 0.78 | NPC1 (0.72) | SMYD3NPC1KMT2ARAB9AMEN1 | |
| SCHEMBL9967836 | 0.76 | KMT2A (0.65) | SMYD3NPC1KMT2ARAB9AMEN1 | |
| SCHEMBL14640451 | 0.76 | DRD2 (0.67) | KMT2AMEN1 | |
| SCHEMBL14640450 | 0.76 | RAB9A (0.52) | NPC1KMT2ARAB9AMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007011760-A2 | INHIBITORS OF MITOTIC KINESIN | KALYPSYS, INC. (US) | 2007-01-25 | — | — | WO | disclosed |