Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.42 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | JAK1 | P23458 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | USP30 | Q70CQ3 | 4/20 | 0.40 |
| ▸ | TACR1 | P25103 | 1/20 | 0.40 |
| ▸ | STS | P08842 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13944382 | 0.88 | KDM4E (0.43) | GPR119JAK2JAK1KDM4EPKM | |
| SCHEMBL6490546 | 0.75 | GPR119 (0.48) | GPR119JAK2JAK1KDM4EPKM | |
| SCHEMBL16002483 | 0.75 | GPR119 (0.47) | GPR119JAK2JAK1KDM4EPKM | |
| SCHEMBL14039529 | 0.72 | GPR119 (0.53) | GPR119JAK2JAK1KDM4EPKM | |
| SCHEMBL2227245 | 0.70 | GPR119 (0.47) | GPR119JAK2JAK1KDM4EPKM | |
| SCHEMBL7712465 | 0.70 | GPR119 (0.56) | GPR119JAK2JAK1KDM4EPKM | |
| SCHEMBL3062560 | 0.69 | GPR119 (0.48) | GPR119JAK2JAK1KDM4EPKM | |
| SCHEMBL29960446 | 0.69 | GPR119 (0.48) | GPR119JAK2JAK1KDM4EPKM | |
| SCHEMBL29960667 | 0.69 | TERT (0.48) | GPR119JAK2JAK1KDM4EPKM | |
| SCHEMBL2078377 | 0.69 | GPR119 (0.50) | GPR119JAK2JAK1KDM4EPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007007072-A1 | 5-HTX MODULATORS | BIO-MEDISINSK INNOVASJON AS (NO) | 2007-01-18 | — | — | WO | disclosed |