Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | F10 | P00742 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18506590 | 0.97 | CA2 (0.49) | CA2TSHRSMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL12175416 | 0.94 | CA2 (0.49) | CA2TSHRSMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL470113 | 0.90 | CA2 (0.54) | CA2TSHRSMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL27292255 | 0.89 | CA2 (0.48) | CA2TSHRSMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL3280990 | 0.85 | CA2 (0.36) | CA2TSHRSMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL25959864 | 0.85 | CA2 (0.49) | CA2TSHRSMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL15928442 | 0.85 | SMN1; SMN2 (0.59) | CA2TSHRSMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL15928604 | 0.85 | SMN1; SMN2 (0.59) | CA2TSHRSMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL16843197 | 0.85 | SMN1; SMN2 (0.59) | CA2TSHRSMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL7071546 | 0.83 | ALDH1A1 (0.59) | CA2TSHRSMN1; SMN2ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1907560-B1 | COMPOUNDS AND METHODS FOR LABELING OLIGONUCLEOTIDES | INTEGRATED DNA TECH INC (US) | 2013-01-23 | — | — | EP | disclosed |
| US-20110071147-A1 | 4-AMINO-THIENO[3,2-C]PYRIDINE-7-CARBOXYLIC ACID AMIDES | LUK KIN-CHUN | 2011-03-24 | — | — | US | disclosed |
| US-20110071147-A1 | 4-AMINO-THIENO[3,2-C]PYRIDINE-7-CARBOXYLIC ACID AMIDES | LUK KIN-CHUN | 2011-03-24 | — | — | US | disclosed |
| US-20100087634-A1 | Fluorous Oligonucleotide Reagents and Affinity Purification of Oligonucleotides | BERRY & ASSOCIATES, INC. (US) | 2010-04-08 | — | — | US | disclosed |
| EP-1917015-A1 | NOVEL 4-AMINO-THIENO[3,2-C]PYRIDINE-7-CARBOXYLIC ACID AMIDES | F.HOFFMANN-LA ROCHE AG (CH) | 2008-05-07 | — | — | EP | disclosed |
| US-20070218490-A1 | NUCLEIC ACID MONOMERS WITH 2'-CHEMICAL MOIETIES | INTEGRATED DNA TECHNOLOGIES, INC. (US) | 2007-09-20 | — | — | US | disclosed |
| WO-2007106907-A2 | NUCLEIC ACID MONOMERS WITH 2'-CHEMICAL MOIETIES | INTEGRATED DNA TECHNOLOGIES, INC. (US) | 2007-09-20 | — | — | WO | disclosed |
| US-20070218490-A1 | NUCLEIC ACID MONOMERS WITH 2'-CHEMICAL MOIETIES | INTEGRATED DNA TECHNOLOGIES, INC. (US) | 2007-09-20 | — | — | US | disclosed |
| WO-2007019884-A1 | NOVEL 4-AMINO-THIENO[3,2-C]PYRIDINE-7-CARBOXYLIC ACID AMIDES | F. HOFFMANN-LA ROCHE AG (CH) | 2007-02-22 | — | — | WO | disclosed |
| WO-2007019884-A1 | NOVEL 4-AMINO-THIENO[3,2-C]PYRIDINE-7-CARBOXYLIC ACID AMIDES | F. HOFFMANN-LA ROCHE AG (CH) | 2007-02-22 | — | — | WO | disclosed |
| US-20050256154-A1 | 4-Amino-thieno[3,2-c]pyridine-7-carboxylic acid amides | LUK KIN-CHUN | 2005-11-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070218490-A1 | NUCLEIC ACID MONOMERS WITH 2'-CHEMICAL MOIETIES | POLRMT, RNGTT, POLM | CA2 2212/4885TSHR 3599/4885SMN1; SMN2 3058/4885 |
| US-20100087634-A1 | Fluorous Oligonucleotide Reagents and Affinity Purification of Oligonucleotides | DCLRE1B, POLM, FBL | CA2 3558/4885TSHR 628/4885SMN1; SMN2 3305/4885 |
| US-20050256154-A1 | 4-Amino-thieno[3,2-c]pyridine-7-carboxylic acid amides | FGFR3, FGFR4, FGFR1 | CA2 2080/4885TSHR 1645/4885SMN1; SMN2 3141/4885 |
| US-20110071147-A1 | 4-AMINO-THIENO[3,2-C]PYRIDINE-7-CARBOXYLIC ACID AMIDES | FGFR3, FGFR4, FGFR1 | CA2 2080/4885TSHR 1645/4885SMN1; SMN2 3141/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.