Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL361678 | 0.75 | PDPK1 (0.39) | MAPTHTTPTK2 | |
| SCHEMBL4106173 | 0.72 | DPP4 (0.43) | MAPTHTTPTK2 | |
| SCHEMBL14536607 | 0.71 | ADORA2A (0.44) | MAPTHTT | |
| SCHEMBL23730112 | 0.62 | TLR8 (0.53) | — | |
| SCHEMBL4830696 | 0.60 | NOS1 (0.37) | MAPTHTTPTK2 | |
| SCHEMBL10803369 | 0.59 | SLC2A1 (0.44) | MAPTHTTPTK2 | |
| SCHEMBL3837505 | 0.59 | PNP (0.48) | MAPT | |
| SCHEMBL19964519 | 0.59 | HTT (0.52) | MAPTHTTPTK2 | |
| SCHEMBL23530790 | 0.59 | ALDH1A1 (0.44) | MAPTHTT | |
| SCHEMBL19661001 | 0.57 | HTT (0.44) | MAPTHTTPTK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8354532-B2 | Pyrrolo [2,3-D] pyrimidines as non-nucleoside reverse transcriptase inhibitors for treatment of HIV | ARDEA BIOSCIENCES, INC. (US) | 2013-01-15 | — | — | US | disclosed |