Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADK | P55263 | 1/20 | 0.52 |
| ▸ | SRC | P12931 | 12/20 | 0.51 |
| ▸ | EGFR | P00533 | 9/20 | 0.51 |
| ▸ | ABL1 | P00519 | 9/20 | 0.49 |
| ▸ | ABL2 | P42684 | 8/20 | 0.49 |
| ▸ | RIPK2 | O43353 | 4/20 | 0.48 |
| ▸ | IGF1R | P08069 | 2/20 | 0.47 |
| ▸ | LCK | P06239 | 2/20 | 0.46 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.46 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.46 |
| ▸ | PAK4 | O96013 | 1/20 | 0.46 |
| ▸ | FYN | P06241 | 1/20 | 0.46 |
| ▸ | CSF1R | P07333 | 1/20 | 0.46 |
| ▸ | RET | P07949 | 1/20 | 0.46 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.46 |
| ▸ | PRKACA | P17612 | 1/20 | 0.46 |
| ▸ | FLT1 | P17948 | 1/20 | 0.46 |
| ▸ | LTK | P29376 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24072104 | 0.86 | RIPK2 (0.61) | ADKSRCEGFRABL1ABL2 | |
| SCHEMBL10261381 | 0.86 | FGR (0.57) | ADKSRCEGFRABL1ABL2 | |
| SCHEMBL19264162 | 0.84 | SRC (0.61) | ADKSRCEGFRABL1ABL2 | |
| SCHEMBL10261916 | 0.82 | ADK (0.55) | ADKSRCEGFRABL1ABL2 | |
| SCHEMBL29999095 | 0.82 | MTOR (0.55) | ADKSRCEGFRABL1ABL2 | |
| SCHEMBL19563041 | 0.82 | ADK (0.55) | ADKSRCEGFRABL1ABL2 | |
| SCHEMBL24650661 | 0.82 | MTOR (0.55) | ADKSRCEGFRABL1ABL2 | |
| SCHEMBL14643787 | 0.82 | ADK (0.52) | ADKSRCEGFRABL1ABL2 | |
| SCHEMBL25048564 | 0.82 | RIPK2 (0.44) | ADKSRCEGFRABL1ABL2 | |
| SCHEMBL6926802 | 0.82 | SRC (0.51) | SRCEGFRABL1ABL2RIPK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022212326-A1 | NEK7 INHIBITORS | Halia Therapeutics, Inc. (US) | 2022-10-06 | — | — | WO | disclosed |
| US-20130018038-A1 | CHEMICAL COMPOUNDS | GLAXOSMITHKLINE LLC | 2013-01-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130018038-A1 | CHEMICAL COMPOUNDS | BRCA1, IRS1, IGF1R | ADK 1509/4885SRC 2497/4885EGFR 49/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.