Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.34 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | LTA4H | P09960 | 1/20 | 0.32 |
| ▸ | NOS1 | P29475 | 2/20 | 0.32 |
| ▸ | NOS2 | P35228 | 2/20 | 0.32 |
| ▸ | NOS3 | P29474 | 1/20 | 0.32 |
| ▸ | GFPT1 | Q06210 | 1/20 | 0.32 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL111171 | 1.00 | KIF11 (0.43) | KIF11SMN1; SMN2ITGB1ITGA4CA1 | |
| SCHEMBL111173 | 1.00 | KIF11 (0.43) | KIF11SMN1; SMN2ITGB1ITGA4CA1 | |
| SCHEMBL111172 | 1.00 | KIF11 (0.43) | KIF11SMN1; SMN2ITGB1ITGA4CA1 | |
| SCHEMBL12438515 | 1.00 | KIF11 (0.43) | KIF11SMN1; SMN2ITGB1ITGA4CA1 | |
| Hydrochloric Acid SCHEMBL1565157 | 0.98 | KIF11 (0.42) | KIF11SMN1; SMN2ITGB1ITGA4CA1 | |
| Hydrochloric Acid SCHEMBL2801871 | 0.98 | KIF11 (0.42) | KIF11SMN1; SMN2ITGB1ITGA4CA1 | |
| Hydrochloric Acid SCHEMBL1565156 | 0.98 | KIF11 (0.42) | KIF11SMN1; SMN2ITGB1ITGA4CA1 | |
| Hydrochloric Acid SCHEMBL29401888 | 0.98 | KIF11 (0.42) | KIF11SMN1; SMN2ITGB1ITGA4CA1 | |
| Hydrochloric Acid SCHEMBL1819809 | 0.98 | KIF11 (0.42) | KIF11SMN1; SMN2ITGB1ITGA4CA1 | |
| Water SCHEMBL28591945 | 0.98 | KIF11 (0.42) | KIF11SMN1; SMN2ITGB1ITGA4CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250009706-A1 | COMPOSITIONS AND METHODS FOR TREATING OPIOID DEPENDENCE AND WITHDRAWAL | CASE WESTERN RESERVE UNIVERSITY | 2025-01-09 | — | — | US | claimed |
| US-12083089-B2 | Compositions and methods for stimulating ventilatory and/or respiratory drive | CASE WESTERN RESERVE UNIVERSITY (US) | 2024-09-10 | — | — | US | claimed |
| US-12064410-B2 | Compositions and methods for stimulating ventilatory and/or respiratory | CASE WESTERN RESERVE UNIVERSITY (US) | 2024-08-20 | — | — | US | claimed |
| EP-4373484-A1 | COMPOSITIONS AND METHODS FOR TREATING OPIOID DEPENDENCE AND WITHDRAWAL | CASE WESTERN RESERVE UNIVERSITY (US) | 2024-05-29 | — | — | EP | claimed |
| US-20240139140-A9 | COMPOSITIONS AND METHODS FOR STIMULATING VENTILATORY AND/OR RESPIRATORY DRIVE | CASE WESTERN RESERVE UNIVERSITY | 2024-05-02 | — | — | US | claimed |
| WO-2023003810-A1 | COMPOSITIONS AND METHODS FOR TREATING OPIOID DEPENDENCE AND WITHDRAWAL | CASE WESTERN RESERVE UNIVERSITY (US) | 2023-01-26 | — | — | WO | claimed |
| US-20220273604-A1 | COMPOSITIONS AND METHODS FOR STIMULATING VENTILATORY AND/OR RESPIRATORY DRIVE | UNIV CASE WESTERN RESERVE (US) | 2022-09-01 | — | — | US | claimed |
| US-12486241-B2 | Cystine diamide analogs for cystinuria | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2025-12-02 | — | — | US | disclosed |
| US-20250009706-A1 | COMPOSITIONS AND METHODS FOR TREATING OPIOID DEPENDENCE AND WITHDRAWAL | CASE WESTERN RESERVE UNIVERSITY | 2025-01-09 | — | — | US | disclosed |
| US-12083089-B2 | Compositions and methods for stimulating ventilatory and/or respiratory drive | CASE WESTERN RESERVE UNIVERSITY (US) | 2024-09-10 | — | — | US | disclosed |
| US-12064410-B2 | Compositions and methods for stimulating ventilatory and/or respiratory | CASE WESTERN RESERVE UNIVERSITY (US) | 2024-08-20 | — | — | US | disclosed |
| EP-4373484-A1 | COMPOSITIONS AND METHODS FOR TREATING OPIOID DEPENDENCE AND WITHDRAWAL | CASE WESTERN RESERVE UNIVERSITY (US) | 2024-05-29 | — | — | EP | disclosed |
| US-20240139140-A9 | COMPOSITIONS AND METHODS FOR STIMULATING VENTILATORY AND/OR RESPIRATORY DRIVE | CASE WESTERN RESERVE UNIVERSITY | 2024-05-02 | — | — | US | disclosed |
| US-20220273604-A1 | COMPOSITIONS AND METHODS FOR STIMULATING VENTILATORY AND/OR RESPIRATORY DRIVE | UNIV CASE WESTERN RESERVE (US) | 2022-09-01 | — | — | US | disclosed |
| US-9040261-B2 | Compounds as L-cystine crystallization inhibitors and uses thereof | NEW YORK UNIVERSITY (US) | 2015-05-26 | — | — | US | disclosed |
| US-9040261-B2 | Compounds as L-cystine crystallization inhibitors and uses thereof | NEW YORK UNIVERSITY (US) | 2015-05-26 | — | — | US | disclosed |
| US-8450089-B2 | Compounds as L-cystine crystallization inhibitors and uses thereof | NEW YORK UNIVERSITY (US) | 2013-05-28 | — | — | US | disclosed |
| US-8450089-B2 | Compounds as L-cystine crystallization inhibitors and uses thereof | NEW YORK UNIVERSITY (US) | 2013-05-28 | — | — | US | disclosed |
| US-20110177173-A1 | COMPOUNDS AS L-CYSTINE CRYSTALLIZATION INHIBITORS AND USES THEREOF | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2011-07-21 | — | — | US | disclosed |
| WO-2011062640-A1 | COMPOUNDS AS L-CYSTINE CRYSTALLIZATION INHIBITORS AND USES THEREOF | NEW YORK UNIVERSITY (US) | 2011-05-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12486241-B2 | Cystine diamide analogs for cystinuria | CTH, CBS, SLC7A11 | KIF11 4117/4885SMN1; SMN2 4177/4885ITGB1 4751/4885 |
| US-12083089-B2 | Compositions and methods for stimulating ventilatory and/or respiratory drive | OPRM1, OPRK1, OPRD1 | KIF11 2253/4885SMN1; SMN2 1109/4885ITGB1 4614/4885 |
| US-20220273604-A1 | COMPOSITIONS AND METHODS FOR STIMULATING VENTILATORY AND/OR RESPIRATORY DRIVE | OPRM1, OPRK1, OPRD1 | KIF11 2253/4885SMN1; SMN2 1109/4885ITGB1 4614/4885 |
| US-12064410-B2 | Compositions and methods for stimulating ventilatory and/or respiratory | CTH, SLC25A20, CRH | KIF11 3540/4885SMN1; SMN2 581/4885ITGB1 4828/4885 |
| US-20110177173-A1 | COMPOUNDS AS L-CYSTINE CRYSTALLIZATION INHIBITORS AND USES THEREOF | GLS, PKD1, CLIC1 | KIF11 4118/4885SMN1; SMN2 4804/4885ITGB1 3178/4885 |
| US-20250009706-A1 | COMPOSITIONS AND METHODS FOR TREATING OPIOID DEPENDENCE AND WITHDRAWAL | OPRM1, OPRK1, OPRD1 | KIF11 2768/4885SMN1; SMN2 2220/4885ITGB1 4147/4885 |
| US-20240139140-A9 | COMPOSITIONS AND METHODS FOR STIMULATING VENTILATORY AND/OR RESPIRATORY DRIVE | OPRM1, OPRK1, OPRD1 | KIF11 2253/4885SMN1; SMN2 1109/4885ITGB1 4614/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.