Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.67 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.67 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.67 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.67 |
| ▸ | TSHR | P16473 | 6/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.50 |
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15733211 | 0.94 | TSHR (0.65) | CYP2D6CYP19A1CYP2C9CYP2C19TSHR | |
| SCHEMBL19994754 | 0.92 | ALDH1A1 (0.64) | CYP2D6CYP19A1CYP2C9CYP2C19TSHR | |
| SCHEMBL15733096 | 0.92 | CYP2D6 (0.59) | CYP2D6CYP19A1CYP2C9CYP2C19TSHR | |
| SCHEMBL5808886 | 0.89 | ALDH1A1 (0.64) | CYP2D6CYP19A1CYP2C9CYP2C19TSHR | |
| SCHEMBL11332129 | 0.89 | CYP2D6 (0.56) | CYP2D6CYP19A1CYP2C9CYP2C19TSHR | |
| SCHEMBL27519835 | 0.89 | ALDH1A1 (0.66) | CYP2D6CYP19A1CYP2C9CYP2C19TSHR | |
| SCHEMBL28589777 | 0.88 | CYP2D6 (0.55) | CYP2D6CYP19A1CYP2C9CYP2C19TSHR | |
| SCHEMBL14645882 | 0.88 | TSHR (0.67) | CYP2D6CYP19A1CYP2C9CYP2C19TSHR | |
| SCHEMBL14645636 | 0.86 | ALDH1A1 (0.68) | CYP2D6CYP19A1CYP2C9CYP2C19TSHR | |
| SCHEMBL28280218 | 0.86 | ALDH1A1 (0.68) | CYP2D6CYP19A1CYP2C9CYP2C19TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9169198-B2 | Method for the production of 2-amino-5-cyano-N,3-dimethylbenzamide | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-10-27 | — | — | US | disclosed |
| US-20140148611-A1 | METHOD FOR THE PRODUCTION OF 2-AMINO-5-CYANO-N,3-DIMETHYLBENZAMIDE | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-05-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140148611-A1 | METHOD FOR THE PRODUCTION OF 2-AMINO-5-CYANO-N,3-DIMETHYLBENZAMIDE | ALKBH5, ALKBH2, MMAB | CYP2D6 443/4885CYP19A1 1729/4885CYP2C9 302/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.