Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.33 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | RXRA | P19793 | 1/20 | 0.32 |
| ▸ | RXRB | P28702 | 1/20 | 0.32 |
| ▸ | PTAFR | P25105 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15808761 | 0.89 | PTAFR (0.34) | NPC1RAB9APTAFR | |
| SCHEMBL15809151 | 0.86 | KDM4E (0.32) | RXRARXRB | |
| SCHEMBL2422398 | 0.82 | NPC1 (0.34) | NPC1ALDH1A1PLA2G1BNFKB1CASP3 | |
| SCHEMBL15808729 | 0.79 | PTAFR (0.39) | NPC1RAB9ARXRARXRBPTAFR | |
| SCHEMBL2974106 | 0.78 | AKR1C3 (0.37) | NPC1ALDH1A1RAB9AESR2 | |
| SCHEMBL2481681 | 0.78 | CYP2A6 (0.37) | ALDH1A1L3MBTL1ESR2 | |
| SCHEMBL29949127 | 0.77 | ALDH1A1 (0.33) | NPC1ALDH1A1PLA2G1BNFKB1CASP3 | |
| SCHEMBL14645967 | 0.77 | ALDH1A1 (0.33) | NPC1ALDH1A1PLA2G1BNFKB1CASP3 | |
| SCHEMBL15825967 | 0.77 | RXRA (0.32) | RXRARXRB | |
| SCHEMBL14142022 | 0.76 | PTAFR (0.36) | RXRARXRBPTAFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2722345-B1 | CATALYST FOR THE POLYMERISATION OF OLEFINS | BOREALIS AG (AT) | 2018-12-05 | — | — | EP | disclosed |
| EP-2729479-B1 | CATALYSTS | BOREALIS AG (AT) | 2017-09-06 | — | — | EP | disclosed |
| US-9630980-B2 | Asymmetrical ligands | BOREALIS AG (AT) | 2017-04-25 | — | — | US | disclosed |
| US-9567351-B2 | Heterophasic copolymers | BOREALIS AG (AT) | 2017-02-14 | — | — | US | disclosed |
| US-9475890-B2 | Catalyst | BOREALIS AG (AT) | 2016-10-25 | — | — | US | disclosed |
| US-9469700-B2 | Polymerisation process and catalyst | BOREALIS AG (AT) | 2016-10-18 | — | — | US | disclosed |
| EP-2729529-B1 | HETEROPHASIC COPOLYMERS | BOREALIS AG (AT) | 2016-04-27 | — | — | EP | disclosed |
| US-20160024123-A1 | Asymmetrical Ligands | BOREALIS AG (AT) | 2016-01-28 | — | — | US | disclosed |
| US-9187583-B2 | Catalysts | BOREALIS AG (AT) | 2015-11-17 | — | — | US | disclosed |
| US-20150266979-A1 | CATALYST | BOREALIS AG (AT) | 2015-09-24 | — | — | US | disclosed |
| US-20150259442-A1 | POLYMERISATION PROCESS AND CATALYST | BOREALIS AG (AT) | 2015-09-17 | — | — | US | disclosed |
| US-20140221584-A1 | CATALYSTS | BOREALIS AG (AT) | 2014-08-07 | — | — | US | disclosed |
| US-20140206819-A1 | HETEROPHASIC COPOLYMERS | BOREALIS AG (AT) | 2014-07-24 | — | — | US | disclosed |
| EP-2729479-A1 | CATALYSTS | Borealis AG (AT) | 2014-05-14 | — | — | EP | disclosed |
| EP-2729529-A1 | HETEROPHASIC COPOLYMERS | Borealis AG (AT) | 2014-05-14 | — | — | EP | disclosed |
| WO-2014060540-A1 | POLYMERISATION PROCESS AND CATALYST | BOREALIS AG (AT) | 2014-04-24 | — | — | WO | disclosed |
| EP-2722345-A1 | Catalyst | Borealis AG (AT) | 2014-04-23 | — | — | EP | disclosed |
| EP-2722346-A1 | Polymerisation process and catalyst | Borealis AG (AT) | 2014-04-23 | — | — | EP | disclosed |
| WO-2013007650-A1 | CATALYSTS | BOREALIS AG (AT) | 2013-01-17 | — | — | WO | disclosed |
| WO-2013007664-A1 | HETEROPHASIC COPOLYMERS | BOREALIS AG (AT) | 2013-01-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160024123-A1 | Asymmetrical Ligands | CCRL2, AR, CCR2 | NPC1 2122/4885ALDH1A1 2229/4885PLA2G1B 3505/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.