SCHEMBL14647231

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL14647242	0.86	PARP1 (0.51)	PARP1TNK1ALDH1A1MAPTDRD2
	SCHEMBL14647220	0.86	TP53 (0.47)	PARP1MAPTDRD2DRD4TNKS
	SCHEMBL14647224	0.85	DRD4 (0.52)	ALDH1A1MAPTL3MBTL1DRD2DRD4
	SCHEMBL14647223	0.82	SIGMAR1 (0.45)	PARP1ALDH1A1HTR7SIGMAR1
	SCHEMBL14647217	0.81	DRD4 (0.48)	PARP1DRD2DRD4HTR7HTR1A
	SCHEMBL14647175	0.80	MGLL (0.49)	PARP1ALDH1A1MAPT
	SCHEMBL14647115	0.79	PARP1 (0.43)	PARP1DRD4PARP2KCNH2HTR7
	SCHEMBL14647194	0.79	PARP1 (0.47)	PARP1ALDH1A1
	SCHEMBL14647243	0.79	HTR7 (0.47)	PARP1MAPTDRD2DRD4HTR7
	SCHEMBL14647226	0.79	TNKS (0.43)	PARP1TNKSHTR1AHTR2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.