SCHEMBL14647191

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL14647242	0.89	PARP1 (0.51)	DRD4DRD3DRD2PARP1TNK1
	SCHEMBL14647192	0.83	PARP1 (0.46)	DRD4DRD3DRD2PARP1TNK1
	SCHEMBL14647179	0.81	ALDH1A1 (0.50)	PARP1ALDH1A1POLBKDM4EHPGD
	SCHEMBL14647183	0.79	PARP1 (0.46)	DRD4DRD3DRD2PARP1TNK1
	SCHEMBL14647166	0.78	PARP1 (0.49)	DRD4DRD3DRD2HTR1APARP1
	SCHEMBL14647226	0.78	TNKS (0.43)	HTR1APARP1TSHRKMT2ATNKS
	SCHEMBL17400358	0.77	TNKS (0.39)	DRD4DRD3DRD2HTR1APARP1
	SCHEMBL14647187	0.77	DRD4 (0.43)	DRD4DRD3DRD2HTR1APARP1
	SCHEMBL14647231	0.77	PARP1 (0.49)	DRD4DRD3DRD2HTR1APARP1
	SCHEMBL15979574	0.77	PARP1 (0.49)	DRD4DRD2HTR1APARP1TNK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.