SCHEMBL14647264

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL14647245	0.80	SIGMAR1 (0.44)	ALDH1A1
	SCHEMBL14647216	0.79	NPC1 (0.51)	ALDH1A1MLYCD
	SCHEMBL14647123	0.77	PARP1 (0.49)	PARP1ALDH1A1LMNA
	SCHEMBL14647112	0.76	PARP1 (0.46)	PARP1
	SCHEMBL14647126	0.75	ALDH1A1 (0.50)	PARP1ALDH1A1LMNA
	SCHEMBL15721658	0.75	PARP1 (0.46)	PARP1
	SCHEMBL14647263	0.74	PARP1 (0.52)	PARP1ALDH1A1LMNA
	SCHEMBL29893389	0.72	PARP1 (0.50)	PARP1ALDH1A1
	SCHEMBL8863944	0.72	MLYCD (0.60)	NAMPTMLYCD
	SCHEMBL14647150	0.70	PARP1 (0.55)	PARP1ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.