Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 2/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.43 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.41 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | BCR | P11274 | 1/20 | 0.40 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.39 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.39 |
| ▸ | NT5E | P21589 | 1/20 | 0.39 |
| ▸ | ALKBH3 | Q96Q83 | 1/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16852397 | 0.87 | AMY1A (0.51) | CYP11B1CYP11B2AMY1ACD274NPC1 | |
| SCHEMBL17775112 | 0.85 | ESR2 (0.44) | APPCYP2C19DYRK1AABCB1ABL1 | |
| SCHEMBL13156763 | 0.83 | PDE3B (0.37) | CYP11B1CYP11B2RPS6KA3PDK2 | |
| SCHEMBL17775109 | 0.83 | ABL1 (0.43) | APPCYP2C19ABCB1ABL1BCR | |
| SCHEMBL13791163 | 0.81 | DYRK1A (0.50) | CYP11B1CYP11B2DYRK1AABCB1ABL1 | |
| SCHEMBL16184211 | 0.81 | CYP2C19 (0.56) | CYP11B1CYP11B2APPCYP2C19DYRK1A | |
| SCHEMBL14648804 | 0.81 | ESR1 (0.45) | APPCYP2C19ESR2 | |
| SCHEMBL17827773 | 0.80 | APP (0.49) | CYP11B1CYP11B2APPCYP2C19DYRK1A | |
| SCHEMBL16183020 | 0.79 | ACHE (0.52) | CYP11B1CYP11B2APPCYP2C19DYRK1A | |
| SCHEMBL21771748 | 0.79 | AKR1C3 (0.39) | RPS6KA3PDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8652353-B2 | Liquid crystal carbonate and liquid crystal medium containing the same with positive or negative dielectric anisotropy | WOJSKOWA AKADEMIA TECHNICZNA (PL) | 2014-02-18 | — | — | US | disclosed |
| US-20130020532-A1 | Liquid crystal carbonate and liquid crystal medium containing the same with positive or negative dielectric anisotropy | WOJSKOWA AKADEMIA TECHNICZNA (PL) | 2013-01-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130020532-A1 | Liquid crystal carbonate and liquid crystal medium containing the same with positive or negative dielectric anisotropy | HCN2, HCN3, HCN1 | CYP11B1 2344/4885CYP11B2 2689/4885APP 3839/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.