Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | TBXA2R | P21731 | 4/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | FBP1 | P09467 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1082241 | 0.92 | ALDH1A1 (0.49) | TDP1LMNAMAPK1HTTALDH1A1 | |
| SCHEMBL1466023 | 0.84 | LMNA (0.45) | LMNAMAPK1HTTALDH1A1PKM | |
| SCHEMBL1467336 | 0.83 | LMNA (0.44) | LMNAMAPK1HTTALDH1A1L3MBTL1 | |
| SCHEMBL1656632 | 0.77 | TDP1 (0.57) | TDP1LMNAHTTALDH1A1MEN1 | |
| SCHEMBL1074499 | 0.77 | ALDH1A1 (0.52) | LMNAMAPK1HTTALDH1A1MEN1 | |
| SCHEMBL1465590 | 0.77 | LMNA (0.41) | LMNAMAPK1HTTALDH1A1KMT2A | |
| SCHEMBL10784720 | 0.77 | TDP1 (0.70) | TDP1MAPK1HTTALDH1A1MEN1 | |
| SCHEMBL1081632 | 0.76 | HCAR3 (0.49) | TDP1LMNAMAPK1ALDH1A1MEN1 | |
| SCHEMBL2724028 | 0.76 | TDP1 (0.62) | TDP1MAPK1ALDH1A1MEN1KMT2A | |
| SCHEMBL10784998 | 0.75 | TDP1 (0.59) | TDP1MAPK1HTTALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110071197-A1 | BIS-ARYL COMPOUNDS FOR USE AS MEDICAMENTS | BIOLIPOX AB (LV) | 2011-03-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110071197-A1 | BIS-ARYL COMPOUNDS FOR USE AS MEDICAMENTS | LTC4S, LTB4R2, LTB4R | TDP1 4176/4885LMNA 710/4885MAPK1 3622/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.