Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.63 |
| ▸ | HTT | P42858 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.59 |
| ▸ | PKM | P14618 | 1/20 | 0.59 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.58 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.51 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.51 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | HTR7 | P34969 | 2/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | PGR | P06401 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11157739 | 0.96 | MEP1B (0.59) | LMNAMAPK1HTTALDH1A1PKM | |
| SCHEMBL29306675 | 0.86 | MEP1B (0.59) | LMNAMAPK1HTTALDH1A1PKM | |
| SCHEMBL7219827 | 0.86 | MEP1B (0.61) | LMNAALDH1A1PKMMEP1BAKR1C3 | |
| SCHEMBL1822202 | 0.83 | MEP1B (0.65) | LMNAMAPK1ALDH1A1MEP1BAKR1C3 | |
| SCHEMBL3074642 | 0.83 | ALDH1A1 (0.67) | MAPK1ALDH1A1PKMMEP1BAKR1C3 | |
| SCHEMBL4070938 | 0.82 | PRMT1 (0.61) | LMNAMAPK1HTTALDH1A1PKM | |
| SCHEMBL30099024 | 0.82 | MEP1B (0.64) | LMNAALDH1A1PKMMEP1BAKR1C3 | |
| SCHEMBL2678034 | 0.82 | ALDH1A1 (0.62) | LMNAMAPK1ALDH1A1PKMMEP1B | |
| SCHEMBL1465523 | 0.82 | ALDH1A1 (0.87) | LMNAMAPK1HTTALDH1A1PKM | |
| SCHEMBL27913080 | 0.82 | ALDH1A1 (0.55) | LMNAMAPK1HTTALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110071197-A1 | BIS-ARYL COMPOUNDS FOR USE AS MEDICAMENTS | BIOLIPOX AB (LV) | 2011-03-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110071197-A1 | BIS-ARYL COMPOUNDS FOR USE AS MEDICAMENTS | LTC4S, LTB4R2, LTB4R | LMNA 710/4885MAPK1 3622/4885HTT 4465/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.