Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.67 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.58 |
| ▸ | PKM | P14618 | 2/20 | 0.58 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.57 |
| ▸ | FABP4 | P15090 | 3/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2678034 | 0.95 | ALDH1A1 (0.62) | ALDH1A1TBXA2RMAPK1MEP1BPKM | |
| SCHEMBL3199069 | 0.90 | ATM (0.64) | ALDH1A1TBXA2RMAPK1MEP1BAKR1C3 | |
| SCHEMBL7756193 | 0.88 | ATM (0.56) | ALDH1A1TBXA2RMAPK1MEP1BPKM | |
| SCHEMBL3075637 | 0.84 | ALDH1A1 (0.75) | ALDH1A1TBXA2RMAPK1PKMFABP4 | |
| SCHEMBL9869950 | 0.84 | ALDH1A1 (0.75) | ALDH1A1TBXA2RMAPK1PKMFABP4 | |
| SCHEMBL29306675 | 0.83 | MEP1B (0.59) | ALDH1A1MAPK1MEP1BPKMAKR1C3 | |
| SCHEMBL11106788 | 0.83 | AKR1C3 (0.68) | ALDH1A1TBXA2RMEP1BAKR1C3 | |
| SCHEMBL1466020 | 0.83 | LMNA (0.63) | ALDH1A1MAPK1MEP1BPKMAKR1C3 | |
| SCHEMBL7219827 | 0.83 | MEP1B (0.61) | ALDH1A1MEP1BPKMAKR1C3L3MBTL1 | |
| SCHEMBL13244191 | 0.82 | ALDH1A1 (0.69) | ALDH1A1TBXA2RMAPK1FABP4ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100261788-A1 | Inhibition of Bid-Induced Cell-Death Using Small Organic Molecules | THE BURNHAM INSTITUTE | 2010-10-14 | — | — | US | disclosed |
| US-7741521-B2 | 4-phenylsulfanyl-phenylamine derivatives used as BH3 Interacting Domain Death Antagonist (BID), for the treatment of neurodegenerative diseases, liver inflammation, multiple sclerosis, heart disease, ischemic injury and for controlling apoptotic cascade | THE BURNHAM INSTITUTE (US) | 2010-06-22 | — | — | US | disclosed |
| US-20070185196-A1 | Inhibitionof bid-induced cell-death using small organic moleculeus | THE BURNHAM INSTITUTE (US) | 2007-08-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070185196-A1 | Inhibitionof bid-induced cell-death using small organic moleculeus | BID, BAD, TMBIM6 | ALDH1A1 4595/4885TBXA2R 4218/4885MAPK1 1548/4885 |
| US-20100261788-A1 | Inhibition of Bid-Induced Cell-Death Using Small Organic Molecules | BID, BAD, TMBIM6 | ALDH1A1 4719/4885TBXA2R 4044/4885MAPK1 2029/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.