Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | CASP7 | P55210 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | MITF | O75030 | 1/20 | 0.39 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | LDLR | P01130 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14667444 | 0.92 | ALOX15 (0.45) | USP2ALOX15CASP1CASP7HSD17B10 | |
| SCHEMBL14667531 | 0.85 | ALDH1A1 (0.41) | ALDH1A1KMT2AHPGDRAB9AMEN1 | |
| SCHEMBL14667464 | 0.85 | HPGD (0.51) | ALDH1A1KMT2AHPGDRAB9AMITF | |
| SCHEMBL14667471 | 0.84 | HDAC3 (0.44) | ALDH1A1KMT2AHPGDMEN1MITF | |
| SCHEMBL15942860 | 0.82 | ALOX15 (0.52) | USP2ALOX15CASP1CASP7HSD17B10 | |
| SCHEMBL14667476 | 0.80 | ALDH1A1 (0.44) | ALDH1A1KMT2AHPGDRAB9AMITF | |
| SCHEMBL14667475 | 0.80 | KMT2A (0.36) | USP2ALOX15CASP1CASP7HSD17B10 | |
| SCHEMBL14667495 | 0.79 | HDAC3 (0.47) | USP2HSD17B10ALDH1A1HPGDMAPT | |
| SCHEMBL14667535 | 0.79 | LNPEP (0.37) | ALDH1A1KMT2AHPGDMEN1MITF | |
| SCHEMBL14667524 | 0.78 | ALDH1A1 (0.39) | ALDH1A1KMT2AHPGDRAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8802448-B2 | Mixed mode ligands | PALL CORPORATION (US) | 2014-08-12 | — | — | US | disclosed |
| US-20130030154-A1 | MIXED MODE LIGANDS | PALL CORPORATION (US) | 2013-01-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130030154-A1 | MIXED MODE LIGANDS | NCL, NECTIN4, NCLN | USP2 2925/4885ALOX15 4665/4885CASP1 4481/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.