Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.40 |
| ▸ | KIT | P10721 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | LCK | P06239 | 1/20 | 0.37 |
| ▸ | SRC | P12931 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14667464 | 0.86 | HPGD (0.51) | ALDH1A1HPGDMITFKLF5KMT2A | |
| SCHEMBL14667443 | 0.81 | MEN1 (0.38) | ALDH1A1HPGDMITFKLF5KMT2A | |
| SCHEMBL15942871 | 0.81 | LMNA (0.43) | ALDH1A1HPGDKMT2ASMN1; SMN2LMNA | |
| SCHEMBL14667471 | 0.81 | HDAC3 (0.44) | ALDH1A1HPGDMITFKLF5KMT2A | |
| SCHEMBL14667445 | 0.80 | USP2 (0.45) | ALDH1A1HPGDMITFKLF5KMT2A | |
| SCHEMBL14667444 | 0.80 | ALOX15 (0.45) | ALDH1A1HPGDMITFKLF5KMT2A | |
| SCHEMBL14667516 | 0.79 | HPGD (0.35) | ALDH1A1HPGDMITFKLF5KMT2A | |
| SCHEMBL14667523 | 0.79 | ALDH1A1 (0.37) | ALDH1A1HPGDMITFKLF5KMT2A | |
| SCHEMBL14667531 | 0.78 | ALDH1A1 (0.41) | ALDH1A1HPGDMITFKLF5KMT2A | |
| SCHEMBL14667495 | 0.78 | HDAC3 (0.47) | ALDH1A1HPGDSMN1; SMN2LMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8802448-B2 | Mixed mode ligands | PALL CORPORATION (US) | 2014-08-12 | — | — | US | disclosed |
| US-20130030154-A1 | MIXED MODE LIGANDS | PALL CORPORATION (US) | 2013-01-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130030154-A1 | MIXED MODE LIGANDS | NCL, NECTIN4, NCLN | ALDH1A1 3975/4885HPGD 3678/4885MITF 4107/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.