Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.67 |
| ▸ | MEN1 | O00255 | 5/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.65 |
| ▸ | POLB | P06746 | 1/20 | 0.65 |
| ▸ | METAP2 | P50579 | 2/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.60 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.59 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1466906 | 0.89 | ALDH1A1 (0.72) | KDM4EALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL29531113 | 0.86 | IKBKB (0.60) | KDM4EALDH1A1MEN1KMT2APOLB | |
| SCHEMBL16127963 | 0.86 | ALDH1A1 (0.69) | KDM4EALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL3556258 | 0.85 | SLC16A3 (0.71) | KDM4EALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL23879580 | 0.84 | ALDH1A1 (0.68) | KDM4EALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL15822907 | 0.84 | ALDH1A1 (0.68) | KDM4EALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL1688339 | 0.84 | METAP2 (0.71) | KDM4EALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL3279765 | 0.84 | ALDH1A1 (0.68) | KDM4EALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL12200779 | 0.84 | CCR2 (0.73) | KDM4EALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL13999327 | 0.84 | ELANE (0.63) | KDM4EALDH1A1MEN1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101646647-A | New methylenebisphenyl compounds useful in the treatment of inflammation | BIOLIPOX AB SE | 2010-02-10 | — | — | CN | disclosed |