Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | ALB | P02768 | 11/20 | 0.35 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.32 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.32 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13445978 | 0.89 | ALB (0.41) | CA2CA9ALBFOLH1MEN1 | |
| SCHEMBL14950991 | 0.81 | FOLH1 (0.32) | FOLH1 | |
| SCHEMBL15706851 | 0.81 | FOLH1 (0.32) | FOLH1 | |
| SCHEMBL22343075 | 0.79 | ACHE (0.38) | FOLH1 | |
| SCHEMBL18412629 | 0.79 | ALDH1A1 (0.55) | ALBFOLH1MEN1KMT2AALDH1A1 | |
| SCHEMBL26346638 | 0.79 | GLP1R (0.40) | ALBFOLH1 | |
| SCHEMBL13887521 | 0.78 | CA2 (0.48) | CA2CA9MEN1KMT2AALDH1A1 | |
| SCHEMBL8477259 | 0.77 | ALDH1A1 (0.39) | ALBFOLH1MEN1KMT2AALDH1A1 | |
| SCHEMBL21964558 | 0.77 | ALDH1A1 (0.39) | ALBFOLH1MEN1KMT2AALDH1A1 | |
| SCHEMBL19646650 | 0.77 | FOLH1 (0.44) | ALBFOLH1MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8921571-B2 | Pyrrolysine analogs | THE OHIO STATE UNIVERSITY (US) | 2014-12-30 | — | — | US | disclosed |
| US-20130035478-A1 | PYRROLYSINE ANALOGS | THE OHIO STATE UNIVERSITY (US) | 2013-02-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130035478-A1 | PYRROLYSINE ANALOGS | UROD, ALDH18A1, HMBS | CA2 4259/4885CA9 2814/4885ALB 3349/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.