Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 12/20 | 0.50 |
| ▸ | NPC1 | O15118 | 11/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.40 |
| ▸ | RELA | Q04206 | 2/20 | 0.40 |
| ▸ | STAT1 | P42224 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16403987 | 0.76 | RAB9A (0.50) | RAB9ANPC1MEN1KMT2AMAPK1 | |
| SCHEMBL16403986 | 0.69 | POLB (0.48) | RAB9ANPC1MEN1KMT2AMAPK1 | |
| SCHEMBL14315443 | 0.69 | RAB9A (0.63) | RAB9ANPC1MEN1KMT2AMAPK1 | |
| SCHEMBL14325787 | 0.68 | RAB9A (0.50) | RAB9ANPC1MEN1KMT2ATDP1 | |
| SCHEMBL14315442 | 0.68 | NPC1 (0.53) | RAB9ANPC1MEN1KMT2AMAPK1 | |
| SCHEMBL14315441 | 0.67 | NPC1 (0.54) | RAB9ANPC1MEN1KMT2AMAPK1 | |
| SCHEMBL14317616 | 0.67 | NPC1 (0.52) | RAB9ANPC1MEN1KMT2AMAPK1 | |
| SCHEMBL16403950 | 0.67 | RAB9A (0.52) | RAB9ANPC1MEN1KMT2AMAPK1 | |
| SCHEMBL16403975 | 0.67 | NPC1 (0.69) | RAB9ANPC1MEN1KMT2AMAPK1 | |
| SCHEMBL16403942 | 0.67 | NPC1 (0.50) | RAB9ANPC1MEN1KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012172438-A9 | COMPOSITIONS AND METHODS FOR MODULATING A KINASE | DYNAMIX PHARMACEUTICALS LTD. (IL) | 2013-02-07 | — | — | WO | disclosed |