Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP1 | P24666 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | METAP2 | P50579 | 1/20 | 0.37 |
| ▸ | METAP1 | P53582 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | FEN1 | P39748 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL38652754 | 0.79 | ACP1 (0.39) | ACP1LMNAKDM4EALDH1A1HTT | |
| SCHEMBL2345799 | 0.77 | MGAM (0.57) | KMT2ALMNAKDM4EALDH1A1F2 | |
| SCHEMBL18796126 | 0.77 | RIPK1 (0.47) | LMNAALDH1A1FEN1HTTL3MBTL1 | |
| SCHEMBL5012780 | 0.76 | CYP1A2 (0.47) | KMT2AMEN1KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL11435205 | 0.75 | ALDH1A1 (0.38) | ALDH1A1F2GLAHPGD | |
| Hydrochloric Acid SCHEMBL10911345 | 0.75 | MGAM (0.56) | KMT2ALMNAKDM4EALDH1A1F2 | |
| SCHEMBL5267380 | 0.75 | ALDH1A1 (0.68) | KMT2ALMNAMEN1KDM4EALDH1A1 | |
| SCHEMBL30392839 | 0.75 | MGAM (0.59) | ACP1KMT2ALMNAMEN1KDM4E | |
| SCHEMBL124592 | 0.75 | MGAM (0.59) | ACP1KMT2ALMNAMEN1KDM4E | |
| SCHEMBL4293313 | 0.74 | PDE4A (0.46) | ACP1METAP2METAP1FEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1678174-B1 | PROCESS FOR PREPARING 7-CHLORO-1-CYCLOPROPYL-6-FLUORO-4-OXO-1,4-DIHYDRO-1,8-NAPHTHYRIDINE-3-CARBOXYLIC ACID | LG LIFE SCIENCES LTD (KR) | 2013-02-13 | — | — | EP | claimed |