Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 4/20 | 0.41 |
| ▸ | S100B | P04271 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14694332 | 1.00 | TP53 (0.41) | TP53S100BMAPTTHRBSMN1; SMN2 | |
| SCHEMBL14694349 | 0.83 | S100B (0.46) | TP53S100BMAPTTHRBSMN1; SMN2 | |
| SCHEMBL14694351 | 0.83 | S100B (0.46) | TP53S100BMAPTTHRBSMN1; SMN2 | |
| SCHEMBL2589705 | 0.80 | KMT2A (0.37) | TP53MAPTTHRBSMN1; SMN2ALDH1A1 | |
| SCHEMBL2589702 | 0.77 | THRB (0.41) | MAPTTHRBSMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL12107154 | 0.77 | THRB (0.41) | MAPTTHRBSMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL825301 | 0.73 | MAPT (0.49) | MAPTTHRBALDH1A1MEN1POLB | |
| SCHEMBL29883561 | 0.73 | MAPT (0.49) | MAPTTHRBALDH1A1MEN1POLB | |
| SCHEMBL10001950 | 0.73 | THRB (0.36) | MAPTTHRBSMN1; SMN2MEN1MAPK1 | |
| SCHEMBL825302 | 0.73 | MAPT (0.49) | MAPTTHRBALDH1A1MEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8475691-B2 | UV-absorbers for ophthalmic lens materials | NOVARTIS AG (CH) | 2013-07-02 | — | — | US | disclosed |
| WO-2013025671-A1 | UV-ABSORBERS FOR OPHTHALMIC LENS MATERIALS | NOVARTIS AG (CH) | 2013-02-21 | — | — | WO | disclosed |
| US-20130043443-A1 | UV-ABSORBERS FOR OPHTHALMIC LENS MATERIALS | NOVARTIS AG (CH) | 2013-02-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130043443-A1 | UV-ABSORBERS FOR OPHTHALMIC LENS MATERIALS | UACA, CRYAA, CRYAB | TP53 2101/4885S100B 641/4885MAPT 378/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.