SCHEMBL1469629

SCHEMBL1469629

C=CC(=O)OCCCC[Si](OC)(OC)OC

nearest known ligand 0.62

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TSHR P16473 9/20 0.62
ALDH1A1 P00352 5/20 0.62
CYP3A4 P08684 2/20 0.62
HPGD P15428 1/20 0.56
TP53 P04637 3/20 0.47
HIF1A Q16665 3/20 0.47
HSD17B10 Q99714 1/20 0.47
THRB P10828 2/20 0.40
ATM Q13315 1/20 0.37
HCAR2 Q8TDS4 3/20 0.36
MAPK1 P28482 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
KDM4E B2RXH2 1/20 0.31
ACHE P22303 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28639221 0.98 TSHR (0.66) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL29402455 0.98 TSHR (0.66) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL2385522 0.98 TSHR (0.66) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL1974553 0.98 TSHR (0.66) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL442439 0.98 TSHR (0.66) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL16286530 0.98 TSHR (0.66) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL4642459 0.98 TSHR (0.66) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL2388478 0.98 TSHR (0.66) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL28894227 0.98 TSHR (0.66) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL29737750 0.98 TSHR (0.66) TSHRALDH1A1CYP3A4HPGDTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 269 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3730121-B1 DENTAL ADHESIVE MATERIAL KIT KURARAY NORITAKE DENTAL INC (JP) 2023-10-25 EP claimed
US-11484477-B2 Dental adhesive material kit KURARAY NORITAKE DENTAL INC. (JP) 2022-11-01 US claimed
CN-107664919-B Method for producing patterned cured product and patterned cured product obtained thereby 三星显示有限公司 2022-10-14 CN claimed
EP-3310792-B1 PROCESS FOR PREPARING AN ACRYLOYLOXYSILANE DOW SILICONES CORP (US) 2021-07-21 EP claimed
US-10744684-B2 Method of preparing patterned cured product and patterned cured product obtained using the method SAMSUNG DISPLAY CO., LTD. (KR) 2020-08-18 US claimed
US-20180029255-A1 METHOD OF PREPARING PATTERNED CURED PRODUCT AND PATTERNED CURED PRODUCT OBTAINED USING THE METHOD SAMSUNG DISPLAY CO., LTD. (KR) 2018-02-01 US claimed
EP-2398768-A1 PYRROLIDINE DERIVATIVES AS NK3 RECEPTOR ANTAGONISTS F. Hoffmann-La Roche AG (CH) 2011-12-28 EP claimed
WO-2010094667-A1 PYRROLIDINE DERIVATIVES AS NK3 RECEPTOR ANTAGONISTS F. HOFFMANN-LA ROCHE AG (CH) 2010-08-26 WO claimed
US-20050048200-A1 PROCESS FOR PREPARING AN OPTICAL WAVEGUIDE COMPONENT FROM ACRYLATE/TITANIUM ALKOXIDE COMPOSITE MATERIAL AND THE PREPARED OPTICAL WAVEGUIDE COMPONENT CHANG CHUN PLASTICS CO., LTD. (TW) 2005-03-03 US claimed
US-6852358-B1 Process for preparing an optical waveguide component from acrylate/titanium alkoxide composite material and the prepared optical waveguide component CHANG CHUN PLASTICS CO., LTD. (TW) 2005-02-08 US claimed
EP-4747320-A1 THERMAL-AND UV-CURABLE (METH) ACRYLATE COMPOSITION Henkel AG & Co. KGaA (DE) 2026-05-27 EP disclosed
US-20260139157-A1 THERMAL-AND-UV-CURABLE (METH)ACRYLATE COMPOSITION HENKEL AG & CO KGAA (DE) 2026-05-21 US disclosed
CN-122054878-A Method for manufacturing light-emitting device, negative-type radiation-sensitive composition, cured film, and organic EL device JSR株式会社 2026-05-15 CN disclosed
EP-4725470-A1 CURABLE DENTAL COMPOSITION Kuraray Noritake Dental Inc. (JP) 2026-04-15 EP disclosed
EP-4717249-A1 DENTAL COMPOSITION Shofu Inc. (JP) 2026-04-01 EP disclosed
EP-0430722-A2 Curable insulating material DAINIPPON INK AND CHEMICALS, INC. (JP) 1991-06-05 EP disclosed
US-4884866-A OPTICAL FIBERS DAINIPPON INK AND CHEMICALS, INC. (JP) 1989-12-05 US disclosed
US-4786658-A ACRYLIC ESTER POLYMER, CLADDING FOR OPTICAL FIBERS DAINIPPON INK AND CHEMICALS, INC. (JP) 1988-11-22 US disclosed
US-4749727-A THREE-DIMENSIONAL CROSSLINKING; EPOXIDES, UNSATURATED ALKOXYSILANES; WATER CURABLE KANSAI PAINT CO., LTD. (JP) 1988-06-07 US disclosed
EP-0243605-A2 Fluorine-containing resin composition having a low refractive index DAINIPPON INK AND CHEMICALS, INC. (JP) 1987-11-04 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260139157-A1 THERMAL-AND-UV-CURABLE (METH)ACRYLATE COMPOSITION MAT1A, MAT2B, MAT2A TSHR 2841/4885ALDH1A1 139/4885CYP3A4 3827/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.