SCHEMBL4642459

SCHEMBL4642459

C=CC(=O)OCCCCCCCC[Si](OC)(OC)OC

nearest known ligand 0.66

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TSHR P16473 9/20 0.66
ALDH1A1 P00352 4/20 0.66
CYP3A4 P08684 2/20 0.66
HPGD P15428 1/20 0.55
TP53 P04637 3/20 0.46
HIF1A Q16665 3/20 0.46
HSD17B10 Q99714 1/20 0.46
THRB P10828 2/20 0.39
HCAR2 Q8TDS4 3/20 0.38
ATM Q13315 1/20 0.36
MAPK1 P28482 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
ACHE P22303 4/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28894227 1.00 TSHR (0.66) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL29402455 1.00 TSHR (0.66) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL28639221 1.00 TSHR (0.66) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL29737750 1.00 TSHR (0.66) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL2388478 1.00 TSHR (0.66) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL2385522 1.00 TSHR (0.66) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL1974553 1.00 TSHR (0.66) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL442439 1.00 TSHR (0.66) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL16286530 1.00 TSHR (0.66) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL9947907 1.00 TSHR (0.66) TSHRALDH1A1CYP3A4HPGDTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 177 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3646847-B1 TWO-PASTE TYPE DENTAL CURABLE COMPOSITION KURARAY NORITAKE DENTAL INC (JP) 2025-01-29 EP claimed
EP-3929226-B1 OPTICAL FIBER SUMITOMO ELECTRIC INDUSTRIES (JP) 2025-01-15 EP claimed
EP-4061897-B1 LAMINATE HAVING INORGANIC NANOPARTICLE-CONTAINING WEAR- RESISTANT LAYER AND INORGANIC NANOPARTICLE-CONTAINING RADIATION-CURABLE INK HAVING LOW VISCOSITY 3M INNOVATIVE PROPERTIES COMPANY (US) 2025-01-08 EP claimed
EP-4061896-B1 LAMINATE HAVING INORGANIC NANOPARTICLE-CONTAINING SURFACE LAYER THAT EXHIBITS APPEARANCE WITH LOW GLOSS AND INORGANIC NANOPARTICLE-CONTAINING RADIATION-CURABLE INK 3M INNOVATIVE PROPERTIES COMPANY (US) 2025-01-08 EP claimed
EP-4035649-B1 DENTAL ADHESIVE COMPOSITION 3M INNOVATIVE PROPERTIES COMPANY (US) 2023-07-26 EP claimed
CN-115960359-A Organic silicon treating agent, preparation method thereof and powder containing organic silicon treating agent 广州硅碳新材料有限公司 2023-04-14 CN claimed
EP-4061897-A1 LAMINATE HAVING INORGANIC NANOPARTICLE-CONTAINING WEAR- RESISTANT LAYER AND INORGANIC NANOPARTICLE-CONTAINING RADIATION-CURABLE INK HAVING LOW VISCOSITY 3M Innovative Properties Company (US) 2022-09-28 EP claimed
EP-4061896-A1 LAMINATE HAVING INORGANIC NANOPARTICLE-CONTAINING SURFACE LAYER THAT EXHIBITS APPEARANCE WITH LOW GLOSS AND INORGANIC NANOPARTICLE-CONTAINING RADIATION-CURABLE INK 3M Innovative Properties Company (US) 2022-09-28 EP claimed
US-20260069510-A1 DENTAL RESIN-REINFORCED GLASS IONOMER CEMENT COMPOSITION SHOFU INC. (JP) 2026-03-12 US disclosed
US-20260060900-A1 DENTAL COMPOSITE RESIN KIT SHOFU INC. (JP) 2026-03-05 US disclosed
US-12534577-B2 Organopolysiloxane and a composition comprising the same SHIN-ETSU CHEMICAL CO., LTD. (JP) 2026-01-27 US disclosed
US-12528926-B2 Resin composition, secondary coating material for optical fiber, optical fiber, and method for manufacturing optical fiber SUMITOMO ELECTRIC INDUSTRIES, LTD. (JP) 2026-01-20 US disclosed
EP-4155339-B1 ORGANOPOLYSILOXANE AND COMPOSITION CONTAINING SAME SHINETSU CHEMICAL CO (JP) 2025-12-24 EP disclosed
US-20250375358-A1 COMPOSITE RESIN TOOTH CONTAINING NON-CROSSLINKED POLYMER PARTICLES SHOFU INC. (JP) 2025-12-11 US disclosed
US-20140378571-A1 CURABLE COMPOSITION AND USES THEREOF SHOWA DENKO K.K. (JP) 2014-12-25 US disclosed
EP-2813521-A1 CURABLE COMPOSITION AND APPLICATION THEREFOR Showa Denko K.K. (JP) 2014-12-17 EP disclosed
EP-1226807-B1 DENTAL CURABLE COMPOSITION TOKUYAMA CORP (JP) 2008-08-13 EP disclosed
US-6933327-B2 Dental curable composition TOKUYAMA CORPORATION (JP) 2005-08-23 US disclosed
US-20030036582-A1 Dental curable composition TOKUYAMA CORPORATION (JP) 2003-02-20 US disclosed
EP-1226807-A1 DENTAL CURABLE COMPOSITION TOKUYAMA CORPORATION (JP) 2002-07-31 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260069510-A1 DENTAL RESIN-REINFORCED GLASS IONOMER CEMENT COMPOSITION GRIN3A, HBG1, ASIC1 TSHR 3161/4885ALDH1A1 3441/4885CYP3A4 4693/4885
US-20260060900-A1 DENTAL COMPOSITE RESIN KIT BOLA2; BOLA2B, LBR, COL2A1 TSHR 3276/4885ALDH1A1 314/4885CYP3A4 4813/4885
US-12528926-B2 Resin composition, secondary coating material for optical fiber, optical fiber, and method for manufacturing optical fiber SMCHD1, SEM1, TAF1 TSHR 2154/4885ALDH1A1 2003/4885CYP3A4 3003/4885
US-12534577-B2 Organopolysiloxane and a composition comprising the same COL2A1, COL1A1, SPTBN1 TSHR 3108/4885ALDH1A1 1530/4885CYP3A4 3211/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.