SCHEMBL28639221

SCHEMBL28639221

C=CC(=O)OCCCCCCCCC[Si](OC)(OC)OC

nearest known ligand 0.66

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TSHR P16473 9/20 0.66
ALDH1A1 P00352 4/20 0.66
CYP3A4 P08684 2/20 0.66
HPGD P15428 1/20 0.55
TP53 P04637 3/20 0.46
HIF1A Q16665 3/20 0.46
HSD17B10 Q99714 1/20 0.46
THRB P10828 2/20 0.39
HCAR2 Q8TDS4 3/20 0.38
ATM Q13315 1/20 0.36
MAPK1 P28482 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
ACHE P22303 4/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28894227 1.00 TSHR (0.66) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL29402455 1.00 TSHR (0.66) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL29737750 1.00 TSHR (0.66) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL2388478 1.00 TSHR (0.66) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL2385522 1.00 TSHR (0.66) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL1974553 1.00 TSHR (0.66) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL4642459 1.00 TSHR (0.66) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL442439 1.00 TSHR (0.66) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL16286530 1.00 TSHR (0.66) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL9947907 1.00 TSHR (0.66) TSHRALDH1A1CYP3A4HPGDTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3646847-B1 TWO-PASTE TYPE DENTAL CURABLE COMPOSITION KURARAY NORITAKE DENTAL INC (JP) 2025-01-29 EP claimed
US-20250000747-A1 SEPARATE-PACK TYPE DENTAL CURABLE COMPOSITION KURARAY NORITAKE DENTAL INC. (JP) 2025-01-02 US claimed
EP-4413967-A1 DIVIDED DENTAL CURING COMPOSITION Kuraray Noritake Dental Inc. (JP) 2024-08-14 EP claimed
CN-110785159-B Dual paste type curable dental composition 可乐丽则武齿科株式会社 2023-06-09 CN claimed
WO-2023058771-A1 DIVIDED DENTAL CURING COMPOSITION クラレノリタケデンタル株式会社 2023-04-13 WO claimed
US-11400030-B2 Two-paste dental curable composition KURARAY NORITAKE DENTAL INC. (JP) 2022-08-02 US claimed
EP-4725470-A1 CURABLE DENTAL COMPOSITION Kuraray Noritake Dental Inc. (JP) 2026-04-15 EP disclosed
EP-4717249-A1 DENTAL COMPOSITION Shofu Inc. (JP) 2026-04-01 EP disclosed
US-20260083642-A1 DENTAL COMPOSITION SHOFU INC (JP) 2026-03-26 US disclosed
EP-4696297-A1 COMPOSITE MATERIAL FOR DENTAL CUTTING Yamakin Co.,Ltd. (JP) 2026-02-18 EP disclosed
EP-4563609-A1 PHOTOCURABLE COMPOSITION, CURED PRODUCT OF SAME, AND COATED ARTICLE SHIN-ETSU CHEMICAL CO., LTD. (JP) 2025-06-04 EP disclosed
CN-119585328-A Photocurable composition, cured product thereof, and coated article 信越化学工业株式会社 2025-03-07 CN disclosed
US-20250032366-A1 DENTAL CURABLE COMPOSITION KURARAY NORITAKE DENTAL INC. (JP) 2025-01-30 US disclosed
US-20220288550-A1 HOLLOW PARTICLES AND USE THEREOF SEKISUI PLASTICS CO., LTD. (JP) 2022-09-15 US disclosed
EP-4056163-A1 DENTAL ADHESIVE COMPOSITION EXCELLENT IN STORAGE STABILITY Shofu Inc. (JP) 2022-09-14 EP disclosed
EP-4056164-A1 PHOTOCURABLE COMPOSITION EXCELLENT IN CURING DEPTH Shofu Inc. (JP) 2022-09-14 EP disclosed
US-11400030-B2 Two-paste dental curable composition KURARAY NORITAKE DENTAL INC. (JP) 2022-08-02 US disclosed
US-11369935-B2 Hollow particles and use thereof SEKISUI PLASTICS CO., LTD. (JP) 2022-06-28 US disclosed
CN-109890344-B Subpackaged dental adhesive 可乐丽则武齿科株式会社 2022-02-22 CN disclosed
CN-113491636-A Dental composition characterized by index of amount of silane coupling agent blended 株式会社松风 2021-10-12 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250000747-A1 SEPARATE-PACK TYPE DENTAL CURABLE COMPOSITION CAD, CCDC6, CALCOCO2 TSHR 4606/4885ALDH1A1 61/4885CYP3A4 4044/4885
US-20250032366-A1 DENTAL CURABLE COMPOSITION H1-0, COL1A1, CHAF1B TSHR 4352/4885ALDH1A1 1530/4885CYP3A4 3913/4885
US-11400030-B2 Two-paste dental curable composition CAD, DNMT3A, DNMT3B TSHR 4487/4885ALDH1A1 1331/4885CYP3A4 4829/4885
US-20260083642-A1 DENTAL COMPOSITION TAS2R42, COL2A1, TAS2R1 TSHR 1588/4885ALDH1A1 1319/4885CYP3A4 4710/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.