Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 9/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.66 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.66 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 3/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 4/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28894227 | 1.00 | TSHR (0.66) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL29402455 | 1.00 | TSHR (0.66) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL28639221 | 1.00 | TSHR (0.66) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL29737750 | 1.00 | TSHR (0.66) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL2388478 | 1.00 | TSHR (0.66) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL2385522 | 1.00 | TSHR (0.66) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL4642459 | 1.00 | TSHR (0.66) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL442439 | 1.00 | TSHR (0.66) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL16286530 | 1.00 | TSHR (0.66) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL9947907 | 1.00 | TSHR (0.66) | TSHRALDH1A1CYP3A4HPGDTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 203 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3646847-B1 | TWO-PASTE TYPE DENTAL CURABLE COMPOSITION | KURARAY NORITAKE DENTAL INC (JP) | 2025-01-29 | — | — | EP | claimed |
| US-20250009607-A1 | DENTAL COMPOSITION AND METHOD OF PRODUCTION THEREOF, AND SURFACE-TREATED FILLER FOR DENTAL USE | KURARAY NORITAKE DENTAL INC. (JP) | 2025-01-09 | — | — | US | claimed |
| US-20250000747-A1 | SEPARATE-PACK TYPE DENTAL CURABLE COMPOSITION | KURARAY NORITAKE DENTAL INC. (JP) | 2025-01-02 | — | — | US | claimed |
| EP-4464301-A1 | DENTAL COMPOSITION, METHOD FOR MANUFACTURING SAME, AND DENTAL SURFACE-TREATED FILLER | Kuraray Noritake Dental Inc. (JP) | 2024-11-20 | — | — | EP | claimed |
| EP-4413967-A1 | DIVIDED DENTAL CURING COMPOSITION | Kuraray Noritake Dental Inc. (JP) | 2024-08-14 | — | — | EP | claimed |
| WO-2023136337-A1 | DENTAL COMPOSITION, METHOD FOR MANUFACTURING SAME, AND DENTAL SURFACE-TREATED FILLER | クラレノリタケデンタル株式会社 | 2023-07-20 | — | — | WO | claimed |
| CN-110785159-B | Dual paste type curable dental composition | 可乐丽则武齿科株式会社 | 2023-06-09 | — | — | CN | claimed |
| WO-2023058771-A1 | DIVIDED DENTAL CURING COMPOSITION | クラレノリタケデンタル株式会社 | 2023-04-13 | — | — | WO | claimed |
| US-11400030-B2 | Two-paste dental curable composition | KURARAY NORITAKE DENTAL INC. (JP) | 2022-08-02 | — | — | US | claimed |
| US-7851547-B2 | Curable composition and coated article | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2010-12-14 | — | — | US | claimed |
| EP-1826239-B1 | Curable composition and coated article | SHINETSU CHEMICAL CO (JP) | 2009-08-26 | — | — | EP | claimed |
| EP-4725470-A1 | CURABLE DENTAL COMPOSITION | Kuraray Noritake Dental Inc. (JP) | 2026-04-15 | — | — | EP | disclosed |
| EP-4717249-A1 | DENTAL COMPOSITION | Shofu Inc. (JP) | 2026-04-01 | — | — | EP | disclosed |
| US-20260083644-A1 | METHOD FOR PRODUCING DENTAL POLYMERIZABLE COMPOSITION OR DENTAL POLYMERIZABLE COMPOSITION INTERMEDIATE | SHOFU INC (JP) | 2026-03-26 | — | — | US | disclosed |
| US-20260083642-A1 | DENTAL COMPOSITION | SHOFU INC (JP) | 2026-03-26 | — | — | US | disclosed |
| EP-1914259-A1 | Primer composition and coated article | Shin-Etsu Chemical Co., Ltd. (JP) | 2008-04-23 | — | — | EP | disclosed |
| US-20070219298-A1 | Curable composition and coated article | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2007-09-20 | — | — | US | disclosed |
| US-20070212557-A1 | Curable composition and coated article | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2007-09-13 | — | — | US | disclosed |
| EP-1826239-A1 | Curable composition and coated article | Shin-Etsu Chemical Co., Ltd. (JP) | 2007-08-29 | — | — | EP | disclosed |
| EP-1826233-A1 | Curable composition and coated article | Shin-Etsu Chemical Co., Ltd. (JP) | 2007-08-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250000747-A1 | SEPARATE-PACK TYPE DENTAL CURABLE COMPOSITION | CAD, CCDC6, CALCOCO2 | TSHR 4606/4885ALDH1A1 61/4885CYP3A4 4044/4885 |
| US-20260083644-A1 | METHOD FOR PRODUCING DENTAL POLYMERIZABLE COMPOSITION OR DENTAL POLYMERIZABLE COMPOSITION INTERMEDIATE | ARCN1, LBR, POLL | TSHR 3634/4885ALDH1A1 2312/4885CYP3A4 2914/4885 |
| US-20250009607-A1 | DENTAL COMPOSITION AND METHOD OF PRODUCTION THEREOF, AND SURFACE-TREATED FILLER FOR DENTAL USE | CAD, SEM1, CAPZA1 | TSHR 3083/4885ALDH1A1 382/4885CYP3A4 4215/4885 |
| US-11400030-B2 | Two-paste dental curable composition | CAD, DNMT3A, DNMT3B | TSHR 4487/4885ALDH1A1 1331/4885CYP3A4 4829/4885 |
| US-20260083642-A1 | DENTAL COMPOSITION | TAS2R42, COL2A1, TAS2R1 | TSHR 1588/4885ALDH1A1 1319/4885CYP3A4 4710/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.