SCHEMBL14698348

SCHEMBL14698348

CCC(=C(C(=O)O)C(=O)c1ncccc1Cl)N(C)C

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 2/20 0.35
RAB9A P51151 2/20 0.35
CTSA P10619 1/20 0.35
KDM4E B2RXH2 6/20 0.34
ALDH1A1 P00352 3/20 0.34
GAA P10253 2/20 0.34
CASP3 P42574 2/20 0.34
SENP8 Q96LD8 2/20 0.34
SENP7 Q9BQF6 2/20 0.34
SENP6 Q9GZR1 2/20 0.34
HTT P42858 1/20 0.34
CTNNB1 P35222 1/20 0.34
WNT3A P56704 1/20 0.34
MAPT P10636 2/20 0.33
ALOX15 P16050 2/20 0.33
L3MBTL1 Q9Y468 2/20 0.33
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
TSHR P16473 1/20 0.33
BLM P54132 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1012187 0.72 CES2 (0.52) RAB9AALDH1A1MAPT
SCHEMBL1012189 0.72 CES2 (0.52) RAB9AALDH1A1MAPT
SCHEMBL9964038 0.72 CTNNB1 (0.48) NPC1RAB9AKDM4EALDH1A1GAA
SCHEMBL15863170 0.71 CYP11B1 (0.42) KDM4EALDH1A1GAACASP3SENP8
SCHEMBL15863169 0.71 CYP11B1 (0.42) KDM4EALDH1A1GAACASP3SENP8
SCHEMBL15863598 0.71 CYP11B1 (0.42) KDM4EALDH1A1GAACASP3SENP8
SCHEMBL19971377 0.68 PIK3C3 (0.33) L3MBTL1
SCHEMBL10514737 0.68 ALDH1A1 (0.50) NPC1RAB9AKDM4EALDH1A1MAPT
SCHEMBL1931609 0.68 CES2 (0.47) NPC1RAB9AKDM4EALDH1A1POLB
SCHEMBL209954 0.68 KDM4E (0.61) RAB9AKDM4EALDH1A1GAAHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140171316-A1 ANTHRANILAMIDE COMPOUNDS AND THEIR USE AS PESTICIDES BASF SE (DE) 2014-06-19 US disclosed
EP-2742038-A1 ANTHRANILAMIDE COMPOUNDS AND THEIR USE AS PESTICIDES BASF SE (DE) 2014-06-18 EP disclosed
EP-2742027-A1 N-THIO-ANTHRANILAMIDE COMPOUNDS AND THEIR USE AS PESTICIDES BASF SE (DE) 2014-06-18 EP disclosed
US-20140162875-A1 N-Thio-Anthranilamide Compounds and Their Use as Pesticides BASF SE (DE) 2014-06-12 US disclosed
WO-2013024004-A1 N-THIO-ANTHRANILAMIDE COMPOUNDS AND THEIR USE AS PESTICIDES BASF SE (DE) 2013-02-21 WO disclosed
WO-2013024006-A1 ANTHRANILAMIDE COMPOUNDS AND THEIR USE AS PESTICIDES BASF SE (DE) 2013-02-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140162875-A1 N-Thio-Anthranilamide Compounds and Their Use as Pesticides ANTXR2, NIT2, TXN NPC1 4483/4885RAB9A 2088/4885CTSA 3288/4885
US-20140171316-A1 ANTHRANILAMIDE COMPOUNDS AND THEIR USE AS PESTICIDES ANTXR2, NQO2, AAAS NPC1 4767/4885RAB9A 1446/4885CTSA 2612/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.