Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2086910 | 0.75 | SLC6A12 (0.33) | — | |
| SCHEMBL8931160 | 0.72 | PIK3C3 (0.50) | PIK3C3KMT2A | |
| SCHEMBL6340967 | 0.71 | — | — | |
| SCHEMBL14845241 | 0.69 | CES2 (0.50) | — | |
| SCHEMBL14698348 | 0.68 | NPC1 (0.35) | L3MBTL1 | |
| SCHEMBL3279431 | 0.68 | ALDH1A1 (0.50) | L3MBTL1CRHR1 | |
| SCHEMBL915781 | 0.68 | SMN1; SMN2 (0.48) | LMNAL3MBTL1 | |
| SCHEMBL29378297 | 0.68 | SMN1; SMN2 (0.48) | LMNAL3MBTL1 | |
| SCHEMBL29980176 | 0.67 | NPSR1 (0.45) | KMT2A | |
| SCHEMBL21174039 | 0.67 | NPSR1 (0.45) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3512849-B1 | 7-SUBSTITUTED 1-ARYL-NAPHTHYRIDIN-3-CARBOXAMIDES AND THEIR USE | BAYER AG (DE) | 2021-06-23 | — | — | EP | disclosed |
| EP-3512849-A1 | 7-SUBSTITUTED 1-ARYL-NAPHTHYRIDINE-3-CARBOXYLIC ACID AMIDES AND USE THEREOF | Bayer Aktiengesellschaft (DE) | 2019-07-24 | — | — | EP | disclosed |
| WO-2018050510-A1 | 7-SUBSTITUTED 1-ARYL-NAPHTHYRIDINE-3-CARBOXYLIC ACID AMIDES AND USE THEREOF | BAYER AKTIENGESELLSCHAFT (DE) | 2018-03-22 | — | — | WO | disclosed |
| EP-3296298-A1 | 7-SUBSTITUTED 1-ARYL-NAPHTHYRIDIN-3-CARBOXAMIDES AND THEIR USE | Bayer Pharma Aktiengesellschaft (DE) | 2018-03-21 | — | — | EP | disclosed |