Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.71 |
| ▸ | TSHR | P16473 | 3/20 | 0.71 |
| ▸ | THRB | P10828 | 2/20 | 0.71 |
| ▸ | BLM | P54132 | 2/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.71 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.71 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.71 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.71 |
| ▸ | GABRP | O00591 | 1/20 | 0.71 |
| ▸ | GABRD | O14764 | 1/20 | 0.71 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.71 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.71 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.71 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.71 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.71 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.71 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.71 |
| ▸ | GABRR2 | P28476 | 1/20 | 0.71 |
| ▸ | SLC6A1 | P30531 | 1/20 | 0.71 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Alpha-Ketoglutaric Acid SCHEMBL16412456 | 1.00 | LMNA (0.71) | LMNATSHRTHRBBLMKMT2A | |
| Alpha-Ketoglutaric Acid SCHEMBL1469844 | 0.93 | NFKB1 (0.73) | LMNATSHRTHRBBLMKMT2A | |
| Alpha-Ketoglutaric Acid SCHEMBL20817532 | 0.93 | EGLN1 (0.70) | LMNATSHRTHRBBLMKMT2A | |
| Alpha-Ketoglutaric Acid SCHEMBL1261453 | 0.85 | EGLN1 (0.74) | LMNATSHRTHRBBLMKMT2A | |
| Gamma-Aminobutyric Acid SCHEMBL31280548 | 0.85 | LMNA (0.88) | LMNATSHRTHRBBLMKMT2A | |
| SCHEMBL728986 | 0.85 | — | — | |
| Alpha-Ketoglutaric Acid SCHEMBL9121 | 0.85 | EGLN1 (0.82) | LMNATSHRTHRBBLMKMT2A | |
| Gamma-Aminobutyric Acid SCHEMBL4878 | 0.84 | — | — | |
| Gamma-Aminobutyric Acid SCHEMBL3973563 | 0.84 | LMNA (1.00) | LMNATSHRTHRBBLMKMT2A | |
| Gamma-Aminobutyric Acid SCHEMBL190459 | 0.84 | LMNA (1.00) | LMNATSHRTHRBBLMKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117083388-A | Recombinant polypeptides having acyl-CoA compound reducing activity | 旭化成株式会社 | 2023-11-17 | — | — | CN | claimed |
| US-20240052297-A1 | MESOPHILIC, METHYLOTROPHIC BACTERIA FOR THE PH-INDEPENDENT PRODUCTION OF BIOCHEMICALS | ACIES BIO D.O.O. (SI) | 2024-02-15 | — | — | US | disclosed |
| CN-117500912-A | Recombinant microorganism having diamine-producing ability and process for producing diamine | 旭化成株式会社 | 2024-02-02 | — | — | CN | disclosed |
| CN-117441008-A | Recombinant microorganism and method for producing C6 compound | 旭化成株式会社 | 2024-01-23 | — | — | CN | disclosed |
| CN-117083388-A | Recombinant polypeptides having acyl-CoA compound reducing activity | 旭化成株式会社 | 2023-11-17 | — | — | CN | disclosed |
| CN-109072261-B | Process for producing L-glufosinate | 巴斯夫欧洲公司 | 2023-03-17 | — | — | CN | disclosed |
| CN-113197207-B | Flavoring agent and method for improving flavor of pumpkin leaf taro | 广东省农业科学院蔬菜研究所 | 2021-12-17 | — | — | CN | disclosed |
| CN-113197207-A | Flavoring agent and method for improving flavor of pumpkin leaf taro | 广东省农业科学院蔬菜研究所 | 2021-08-03 | — | — | CN | disclosed |
| CN-112739822-A | Method for improving L-glufosinate-ammonium yield | 巴斯夫欧洲公司 | 2021-04-30 | — | — | CN | disclosed |
| US-20190091300-A1 | METHODS OF TREATING CANCER OF THE CENTRAL NERVOUS SYSTEM | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2019-03-28 | — | — | US | disclosed |
| WO-2015092599-A1 | IMPROVED PROCESS FOR THE PRODUCTION OF GAMMA-AMINOBUTYRIC ACID (GABA) | BASF SE (DE) | 2015-06-25 | — | — | WO | disclosed |
| US-9034319-B2 | Methods of treating cancer of the central nervous system | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2015-05-19 | — | — | US | disclosed |
| US-20110070218-A1 | METHODS OF TREATING CANCER OF THE CENTRAL NERVOUS SYSTEM | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2011-03-24 | — | — | US | disclosed |
| US-7767204-B2 | Method and composition for protecting neuronal tissue from damage induced by elevated glutamate levels | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2010-08-03 | — | — | US | disclosed |
| US-20090304661-A1 | Method And Composition For Proctecting Neuronal Tissue From Damage Induced By Elevated Glutamate Levels | YEDA RESEARCH AND DEVELOPMENT CO. LTD. AT THE WEIZMANN INSTITUTE OF SCEINCE (IL) | 2009-12-10 | — | — | US | disclosed |
| US-20090186358-A1 | Pathway Analysis of Cell Culture Phenotypes and Uses Thereof | WYETH (US) | 2009-07-23 | — | — | US | disclosed |
| US-20080233099-A1 | Method and composition for protecting neuronal tissue from damage induced by elevated glutamate levels | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2008-09-25 | — | — | US | disclosed |
| US-20080233096-A1 | transaminase, dehydrogenase, decarboxylase, ligase as glutamate modifying enzymes and oxaloacetate, pyruvate, NAD+, NADP+, 2-oxohexanedioic acid, 2-oxo-3-sulfopropionate, 2-oxo-3-sulfinopropionic acid, 2-oxo-3-phenylpropionic acid co-factors to enhance brain to blood efflux | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2008-09-25 | — | — | US | disclosed |
| US-7404951-B2 | Method and composition for protecting neuronal tissue from damage induced by elevated glutamate levels | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2008-07-29 | — | — | US | disclosed |
| US-20060024284-A1 | Method and composition for protecting neuronal tissue from damage induced by elevated glutamate levels | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2006-02-02 | — | — | US | disclosed |