Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 5/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.45 |
| ▸ | DRD3 | P35462 | 3/20 | 0.45 |
| ▸ | HRH1 | P35367 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.45 |
| ▸ | DRD2 | P14416 | 2/20 | 0.45 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.45 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.45 |
| ▸ | HTR2A | P28223 | 2/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27260858 | 0.85 | OPRM1 (0.50) | CHRM1SLC6A3SLC6A2DRD3HRH1 | |
| SCHEMBL28018520 | 0.83 | L3MBTL3 (0.56) | CHRM1SLC6A3SLC6A2DRD3HRH1 | |
| SCHEMBL16225988 | 0.81 | ACHE (0.51) | MGLLACHECYP1A2CYP2D6CYP2C9 | |
| SCHEMBL7944686 | 0.77 | ACHE (0.51) | MGLLACHEOPRM1OPRK1CACNA1B | |
| SCHEMBL6983812 | 0.77 | ACHE (0.51) | MGLLACHECHRM1SLC6A3SLC6A2 | |
| SCHEMBL16226399 | 0.77 | ACHE (0.51) | MGLLACHECHRM1SLC6A3SLC6A2 | |
| SCHEMBL12093605 | 0.74 | LMNA (0.48) | TSHRKCNH2LMNAHTTMAPT | |
| SCHEMBL12368436 | 0.73 | OPRM1 (0.49) | CHRM1SLC6A3SLC6A2DRD3HRH1 | |
| SCHEMBL8477673 | 0.73 | ACHE (0.51) | MGLLACHECHRM1SLC6A3SLC6A2 | |
| SCHEMBL1677055 | 0.73 | MEN1 (0.42) | MGLLACHECHRM1SLC6A3SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2346820-B1 | OXYCARBAMOYL COMPOUNDS AND THE USE THEREOF | SHIONOGI & CO (JP) | 2013-02-13 | — | — | EP | disclosed |