Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 3/20 | 0.51 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.50 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.50 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.50 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.50 |
| ▸ | IGF1R | P08069 | 1/20 | 0.47 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.46 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.46 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.46 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.46 |
| ▸ | MGLL | Q99685 | 2/20 | 0.45 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.44 |
| ▸ | P4HB | P07237 | 3/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28880055 | 0.82 | HSD11B1 (0.51) | OPRM1 | |
| SCHEMBL16225988 | 0.81 | ACHE (0.51) | ACHEOPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL6983812 | 0.81 | ACHE (0.51) | ACHEOPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL7275198 | 0.81 | ACHE (0.46) | ACHEOPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL5745201 | 0.81 | L3MBTL3 (0.61) | OPRM1OPRD1OPRK1OPRL1 | |
| Hydrochloric Acid SCHEMBL10797918 | 0.79 | L3MBTL3 (0.59) | OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL16226399 | 0.77 | ACHE (0.51) | ACHEOPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL14699666 | 0.77 | MGLL (0.48) | ACHEOPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL8477673 | 0.77 | ACHE (0.51) | ACHEOPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL14280201 | 0.76 | ACHE (0.71) | ACHEOPRM1OPRD1OPRK1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009151152-A1 | OXYCARBAMOYL COMPOUNDS AND THE USE THEREOF | SHIONOGI & CO., LTD. (JP) | 2009-12-17 | — | — | WO | disclosed |
| US-5683998-A | ANTIINFLAMMATORY AGENTS, ANTIALLERGENS, ANTIPAF AGENTS | TORAY INDUSTRIES, INC. (JP) | 1997-11-04 | — | — | US | disclosed |