SCHEMBL14701183

SCHEMBL14701183

CC(COC(=O)/C(C#N)=C/c1ccc(N(c2ccccc2)c2ccccc2)cc1)OC(=O)/C(C#N)=C/c1ccc(N(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.58

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
IDE P14735 2/20 0.58
MAPT P10636 6/20 0.47
ALDH1A1 P00352 5/20 0.47
KDM4E B2RXH2 2/20 0.47
HPGD P15428 2/20 0.47
MEN1 O00255 4/20 0.46
KMT2A Q03164 4/20 0.46
TP53 P04637 2/20 0.45
RAB9A P51151 1/20 0.45
LMNA P02545 1/20 0.44
MAPK1 P28482 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15371842 0.89 ALDH1A1 (0.56) IDEMAPTALDH1A1KDM4EHPGD
SCHEMBL14701163 0.88 ALDH1A1 (0.59) IDEMAPTALDH1A1KDM4EMEN1
SCHEMBL14701210 0.87 IDE (0.61) IDEMAPTALDH1A1KDM4EMEN1
SCHEMBL14701178 0.86 ALDH1A1 (0.48) IDEMAPTALDH1A1KDM4EMEN1
SCHEMBL14701170 0.85 ALDH1A1 (0.56) IDEMAPTALDH1A1KDM4EMEN1
SCHEMBL15371833 0.85 ALDH1A1 (0.64) MAPTALDH1A1KDM4EHPGDMEN1
SCHEMBL17732453 0.83 IDE (0.48) IDEMAPTALDH1A1KDM4EHPGD
SCHEMBL14701199 0.83 DNM1 (0.58) IDEMAPTALDH1A1KDM4EHPGD
SCHEMBL15491151 0.82 IDE (0.46) IDEMAPTALDH1A1KDM4EHPGD
SCHEMBL14703462 0.82 IDE (0.48) IDEMAPTALDH1A1KDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8664289-B2 Dye and coloring photosensitive composition ADEKA CORPORATION (JP) 2014-03-04 US disclosed
US-8664289-B2 Dye and coloring photosensitive composition ADEKA CORPORATION (JP) 2014-03-04 US disclosed
US-20130041062-A1 DYE AND COLORING PHOTOSENSITIVE COMPOSITION ADEKA CORPORATION (JP) 2013-02-14 US disclosed
US-20130041062-A1 DYE AND COLORING PHOTOSENSITIVE COMPOSITION ADEKA CORPORATION (JP) 2013-02-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130041062-A1 DYE AND COLORING PHOTOSENSITIVE COMPOSITION IK, CRY1, ABCG2 IDE 3612/4885MAPT 458/4885ALDH1A1 155/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.