Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 3/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 7/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 7/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 3/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.36 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | F13A1 | P00488 | 2/20 | 0.32 |
| ▸ | TGM2 | P21980 | 2/20 | 0.32 |
| ▸ | TGM1 | P22735 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | EP300 | Q09472 | 1/20 | 0.32 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.32 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14701275 | 0.79 | THRB (0.35) | CA2PTGS1PTGS2SLC22A12THRB | |
| SCHEMBL7236743 | 0.74 | THRB (0.44) | THRBTGM2 | |
| SCHEMBL27421526 | 0.73 | THRB (0.45) | THRBF13A1TGM2TGM1 | |
| SCHEMBL24609573 | 0.73 | THRB (0.43) | THRBEP300KAT2BKAT8 | |
| SCHEMBL14701278 | 0.71 | THRB (0.35) | THRB | |
| SCHEMBL12242602 | 0.71 | THRB (0.38) | KEAP1NFE2L2THRBTGM2 | |
| SCHEMBL12332753 | 0.71 | THRB (0.44) | KEAP1THRB | |
| SCHEMBL14701285 | 0.70 | ACE2 (0.42) | THRBTGM2 | |
| SCHEMBL14701302 | 0.70 | THRB (0.40) | CA2THRBF13A1TGM2TGM1 | |
| SCHEMBL10033659 | 0.69 | EP300 (0.41) | THRBTGM2EP300KAT2BKAT8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9040225-B2 | Developable bottom antireflective coating composition and pattern forming method using thereof | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2015-05-26 | — | — | US | disclosed |
| US-8715907-B2 | Developable bottom antireflective coating compositions for negative resists | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2014-05-06 | — | — | US | disclosed |
| US-20130040238-A1 | DEVELOPABLE BOTTOM ANTIREFLECTIVE COATING COMPOSITIONS FOR NEGATIVE RESISTS | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2013-02-14 | — | — | US | disclosed |