Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.39 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.39 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.39 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.39 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | ACLY | P53396 | 1/20 | 0.38 |
| ▸ | TERT | O14746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14703823 | 0.94 | ADORA2A (0.43) | ABCG2HPGDADORA2AADORA1GRIN2D | |
| SCHEMBL14701512 | 0.86 | KDM4E (0.39) | ALDH1A1ABCG2KDM4EHPGDPIN1 | |
| SCHEMBL30081962 | 0.85 | TERT (0.49) | ABCG2KDM4EMAPTTERT | |
| SCHEMBL433807 | 0.85 | TERT (0.49) | ABCG2KDM4EMAPTTERT | |
| SCHEMBL14701511 | 0.82 | ABCG2 (0.39) | ALDH1A1ABCG2KDM4EHPGDMAPT | |
| SCHEMBL6514737 | 0.81 | TERT (0.52) | ABCG2TERT | |
| SCHEMBL31456160 | 0.81 | TERT (0.52) | ABCG2TERT | |
| SCHEMBL14703877 | 0.80 | AURKA (0.38) | ALDH1A1KDM4EHPGDGRIN2DGRIN3B | |
| SCHEMBL17687648 | 0.78 | TERT (0.43) | ABCG2KDM4EMAPTTERT | |
| SCHEMBL14701518 | 0.78 | ABCG2 (0.36) | ALDH1A1ABCG2KDM4EHPGDPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9156849-B2 | Application of β-functionalized dihydroxy-chlorins for PDT | BIOLITEC PHARMA MARKETING LTD (MY) | 2015-10-13 | — | — | US | disclosed |
| US-20130041307-A1 | APPLICATION OF BETA-FUNCTIONALIZED DIHYDROXY-CHLORINS FOR PDT | CERAMOPTEC INDUSTRIES, INC. | 2013-02-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130041307-A1 | APPLICATION OF BETA-FUNCTIONALIZED DIHYDROXY-CHLORINS FOR PDT | TK1, DHPS, DLD | ALDH1A1 1123/4885ABCG2 1881/4885KDM4E 1701/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.