Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A1 | P22736 | 2/20 | 0.54 |
| ▸ | MYC | P01106 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | HSPA1A | P0DMV8 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7737462 | 0.91 | NR4A1 (0.65) | NR4A1MYCALDH1A1KDM4EHPGD | |
| SCHEMBL15714711 | 0.79 | ALDH1A1 (0.69) | MYCALDH1A1KDM4EHPGDPKM | |
| Methyl 3,5-Dimethylbenzoate SCHEMBL334346 | 0.78 | CNR2 (0.66) | ALDH1A1KDM4ETDP1POLBMAPT | |
| SCHEMBL70232 | 0.78 | ATM (0.61) | ALDH1A1KDM4ETDP1POLBMAPT | |
| SCHEMBL5786005 | 0.76 | MYC (0.47) | NR4A1MYCALDH1A1KDM4EHPGD | |
| SCHEMBL11362015 | 0.76 | MYC (0.56) | MYCALDH1A1KDM4EHPGDPKM | |
| SCHEMBL18617350 | 0.75 | ALDH1A1 (0.49) | MYCALDH1A1KDM4EHPGDPKM | |
| SCHEMBL31401209 | 0.72 | TP53 (0.66) | ALDH1A1KDM4EHPGDMAPTMEN1 | |
| Methyl 3,5-Dimethylbenzoate SCHEMBL9579696 | 0.72 | TSHR (0.73) | ALDH1A1KDM4EHPGDTDP1POLB | |
| SCHEMBL19386238 | 0.71 | LMNA (0.47) | ALDH1A1KDM4EMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8932842-B2 | Aminopyridine dimer compounds, compositions and related methods for neuronal nitric oxide synthase inhibition | NORTHWESTERN UNIVERSITY (US) | 2015-01-13 | — | — | US | disclosed |
| US-20130040359-A1 | Aminopyridine dimer compounds, compositions and related methods for neuronal nitric oxide synthase inhibition | NORTHWESTERN UNIVERSITY (US) | 2013-02-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130040359-A1 | Aminopyridine dimer compounds, compositions and related methods for neuronal nitric oxide synthase inhibition | NOS2, NOS1, NOS3 | NR4A1 2210/4885MYC 3787/4885ALDH1A1 1362/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.