Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | CRHBP | P24387 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 2/20 | 0.46 |
| ▸ | TACR1 | P25103 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | PTPRC | P08575 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27846776 | 0.82 | MAPK1 (0.57) | ALDH1A1MEN1KMT2AMAPK1SMN1; SMN2 | |
| SCHEMBL13811595 | 0.81 | MEN1 (0.51) | ALDH1A1MEN1KMT2AMAPK1SMN1; SMN2 | |
| SCHEMBL11523079 | 0.79 | MEN1 (0.57) | ALDH1A1MEN1KMT2AMAPK1SMN1; SMN2 | |
| SCHEMBL14712316 | 0.79 | ALDH1A1 (0.60) | ALDH1A1MEN1KMT2AMAPK1SMN1; SMN2 | |
| SCHEMBL13034149 | 0.78 | MEN1 (0.58) | ALDH1A1MEN1KMT2AMAPK1SMN1; SMN2 | |
| SCHEMBL8832072 | 0.77 | ALDH1A1 (0.51) | ALDH1A1MEN1KMT2AMAPK1SMN1; SMN2 | |
| SCHEMBL16017753 | 0.77 | ESR1 (0.52) | ALDH1A1MEN1KMT2AMAPK1SMN1; SMN2 | |
| SCHEMBL3928139 | 0.76 | MEN1 (0.56) | ALDH1A1MEN1KMT2AMAPK1SMN1; SMN2 | |
| SCHEMBL11629539 | 0.76 | MEN1 (0.56) | ALDH1A1MEN1KMT2AMAPK1SMN1; SMN2 | |
| SCHEMBL11526212 | 0.75 | ALDH1A1 (0.49) | ALDH1A1MEN1KMT2AMAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130045952-A1 | ABA Receptor Agonists for Increased Plant Stress Resistance | VAN ANDEL RESEARCH INSTITUTE (US) | 2013-02-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130045952-A1 | ABA Receptor Agonists for Increased Plant Stress Resistance | BROX, AAK1, ADORA3 | ALDH1A1 3422/4885MEN1 4858/4885KMT2A 2708/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.