Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.52 |
| ▸ | THRA | P10827 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | MIF | P14174 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | NAAA | Q02083 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10243854 | 0.84 | ALDH1A1 (0.61) | ALDH1A1L3MBTL1MAPK1KMT2AMAPT | |
| SCHEMBL1828327 | 0.78 | PPARG (0.46) | ALDH1A1KMT2A | |
| SCHEMBL14707337 | 0.77 | ALDH1A1 (0.52) | ALDH1A1L3MBTL1MAPK1KMT2AMEN1 | |
| SCHEMBL17938471 | 0.74 | SMN1; SMN2 (0.44) | ALDH1A1L3MBTL1MAPK1MIFKMT2A | |
| SCHEMBL23142607 | 0.73 | ALDH1A1 (0.61) | ALDH1A1L3MBTL1MAPK1KMT2AMAPT | |
| SCHEMBL19387493 | 0.72 | L3MBTL1 (0.48) | ESR1L3MBTL1KMT2AMEN1MAPT | |
| SCHEMBL2847154 | 0.71 | ALDH1A1 (0.59) | ALDH1A1L3MBTL1MAPK1KMT2AMEN1 | |
| SCHEMBL6685103 | 0.71 | ESR1 (0.74) | ESR1THRATHRBALDH1A1BLM | |
| SCHEMBL6449232 | 0.70 | ALDH1A1 (0.58) | ALDH1A1L3MBTL1MAPK1KMT2AMAPT | |
| SCHEMBL4178623 | 0.70 | ALDH1A1 (0.58) | ALDH1A1L3MBTL1MAPK1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140256694-A1 | STEROID ANTIBIOTIC CONJUGATES | ALLERGAN, INC. (US) | 2014-09-11 | — | — | US | disclosed |
| US-20140256696-A1 | Steroid conjugates | ALLERGAN, INC. (US) | 2014-09-11 | — | — | US | disclosed |
| US-20140256666-A1 | ANTIBIOTIC CONJUGATES WITH NONSTEROIDAL ANTI-INFLAMMATORY DRUGS | ALLERGAN, INC. (US) | 2014-09-11 | — | — | US | disclosed |
| US-20140256660-A1 | ANTIBIOTIC CONJUGATES LINKED WITH STEROID DRUGS | ALLERGAN, INC. (US) | 2014-09-11 | — | — | US | disclosed |
| US-20140256658-A1 | Antibiotic Conjugates | ALLERGAN, INC. (US) | 2014-09-11 | — | — | US | disclosed |
| US-20140256651-A1 | Cyclosporine A steroid conjugates | ALLERGAN, INC. (US) | 2014-09-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140256666-A1 | ANTIBIOTIC CONJUGATES WITH NONSTEROIDAL ANTI-INFLAMMATORY DRUGS | MMP17, NAALAD2, DNPEP | ESR1 2374/4885THRA 4808/4885THRB 4846/4885 |
| US-20140256694-A1 | STEROID ANTIBIOTIC CONJUGATES | CYP17A1, CYP21A2, HSD17B1 | ESR1 641/4885THRA 4300/4885THRB 4202/4885 |
| US-20140256660-A1 | ANTIBIOTIC CONJUGATES LINKED WITH STEROID DRUGS | CYP21A2, CYP17A1, CYP46A1 | ESR1 1402/4885THRA 4303/4885THRB 4266/4885 |
| US-20140256658-A1 | Antibiotic Conjugates | NAALAD2, DNPEP, ENGASE | ESR1 2597/4885THRA 4534/4885THRB 4568/4885 |
| US-20140256696-A1 | Steroid conjugates | CYP21A2, CYP17A1, HSD17B2 | ESR1 664/4885THRA 3688/4885THRB 3237/4885 |
| US-20140256651-A1 | Cyclosporine A steroid conjugates | CYP21A2, CHP1, CYP51A1 | ESR1 4089/4885THRA 3750/4885THRB 4189/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.