Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MGLL | Q99685 | 3/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.38 |
| ▸ | KMO | O15229 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.36 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.36 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | AGXT | P21549 | 1/20 | 0.35 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.35 |
| ▸ | FEN1 | P39748 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.34 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14707690 | 0.78 | ALDH1A1 (0.47) | ALDH1A1MGLLALOX5CYP3A4TDP1 | |
| SCHEMBL4451573 | 0.78 | CYP3A4 (0.55) | MAOAALDH1A1MGLLHDAC8KMO | |
| SCHEMBL321882 | 0.77 | TDP1 (0.50) | ALDH1A1CYP3A4TDP1CYP2C9ESR1 | |
| Hydrochloric Acid SCHEMBL5433165 | 0.76 | CYP3A4 (0.52) | MAOAALDH1A1MGLLHDAC8KMO | |
| SCHEMBL27456368 | 0.76 | CYP3A4 (0.60) | MAOAALDH1A1MGLLHDAC8KMO | |
| SCHEMBL9288104 | 0.75 | TDP1 (0.47) | ALDH1A1CYP3A4TDP1CYP2C9ESR1 | |
| SCHEMBL2606103 | 0.74 | MAOA (0.44) | MAOAALDH1A1MGLLHDAC8KMO | |
| SCHEMBL12621189 | 0.74 | MGLL (0.50) | MAOAALDH1A1MGLLHDAC8KMO | |
| SCHEMBL14244857 | 0.74 | MAOA (0.44) | MAOAALDH1A1MGLLHDAC8KMO | |
| SCHEMBL31189334 | 0.74 | MAOA (0.44) | MAOAALDH1A1MGLLHDAC8KMO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9139765-B2 | Organic electroluminescent device | MERCK PATENT GMBH (DE) | 2015-09-22 | — | — | US | disclosed |
| US-9139765-B2 | Organic electroluminescent device | MERCK PATENT GMBH (DE) | 2015-09-22 | — | — | US | disclosed |
| US-20130046094-A1 | ORGANIC ELECTROLUMINESCENT DEVICE | MERCK PATENT GMBH (DE) | 2013-02-21 | — | — | US | disclosed |
| US-20130046094-A1 | ORGANIC ELECTROLUMINESCENT DEVICE | MERCK PATENT GMBH (DE) | 2013-02-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130046094-A1 | ORGANIC ELECTROLUMINESCENT DEVICE | PIEZO1, L1CAM, OR10J3 | MAOA 482/4885ALDH1A1 131/4885MGLL 1829/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.