Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1471374 | 0.83 | HTR1A (0.38) | — | |
| SCHEMBL1471415 | 0.71 | HDAC4 (0.37) | KDM4EGAAMAPT | |
| SCHEMBL1470738 | 0.67 | HPGD (0.42) | MAPT | |
| SCHEMBL1471418 | 0.67 | HTR1A (0.41) | — | |
| SCHEMBL6201094 | 0.62 | MAPT (0.52) | KDM4EGAAMAPT | |
| SCHEMBL1470996 | 0.62 | MEN1 (0.61) | KDM4EGAAMAPT | |
| SCHEMBL20024596 | 0.60 | CHRM2 (0.55) | KDM4E | |
| SCHEMBL186274 | 0.60 | NOS1 (0.52) | GAA | |
| SCHEMBL3173918 | 0.58 | NOS1 (0.50) | GAA | |
| SCHEMBL8542775 | 0.58 | NOS1 (0.50) | GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7915420-B2 | Aryl piperidine amides | JANSSEN PHARMACEUTICA NV (BE) | 2011-03-29 | — | — | US | claimed |