Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 4/20 | 0.38 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.31 |
| ▸ | TACR1 | P25103 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1471413 | 0.83 | KDM4E (0.32) | — | |
| SCHEMBL1470929 | 0.79 | HTR1A (0.36) | HTR1A | |
| SCHEMBL1471375 | 0.74 | ADRA1D (0.38) | HTR1A | |
| SCHEMBL1470926 | 0.71 | HRH3 (0.43) | HTR1A | |
| SCHEMBL1471527 | 0.69 | HTR1A (0.75) | HTR1A | |
| SCHEMBL1471418 | 0.69 | HTR1A (0.41) | HTR1A | |
| SCHEMBL6387103 | 0.66 | ADRA2A (0.44) | HTR1A | |
| SCHEMBL1473277 | 0.64 | HTR1A (0.52) | HTR1A | |
| SCHEMBL4908913 | 0.62 | HTR1A (0.42) | HTR1A | |
| SCHEMBL5649593 | 0.60 | CA12 (0.46) | MRGPRX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7915420-B2 | Aryl piperidine amides | JANSSEN PHARMACEUTICA NV (BE) | 2011-03-29 | — | — | US | claimed |