Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.53 |
| ▸ | AGXT | P21549 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.38 |
| ▸ | MEF2D | Q14814 | 4/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1471240 | 0.80 | RAB9A (0.47) | MEN1ALDH1A1KMT2AHPGDHTT | |
| Formaldehyde SCHEMBL1471574 | 0.80 | PRMT6 (0.50) | PRMT6AGXTHDAC4MEF2DTRPA1 | |
| Formaldehyde SCHEMBL1471009 | 0.77 | MAPT (0.56) | PRMT6MAPTCYP1A2CYP2C19CYP2C9 | |
| SCHEMBL1471529 | 0.72 | HTR1A (0.64) | PRMT6AGXTTRPA1MAPTALDH1A1 | |
| SCHEMBL1471418 | 0.72 | HTR1A (0.41) | ALDH1A1HTT | |
| SCHEMBL30228501 | 0.71 | PRMT6 (0.62) | PRMT6AGXTTRPA1MAPTMEN1 | |
| SCHEMBL1036548 | 0.71 | PRMT6 (1.00) | PRMT6AGXTHDAC4MEF2DTRPA1 | |
| SCHEMBL19595393 | 0.71 | PRMT6 (0.67) | PRMT6AGXTHDAC4MEF2DTRPA1 | |
| SCHEMBL4576037 | 0.69 | PRMT6 (0.59) | PRMT6AGXTTRPA1MAPTMEN1 | |
| SCHEMBL5621913 | 0.69 | PRMT6 (0.97) | PRMT6AGXTHDAC4MEF2DTRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7915420-B2 | Aryl piperidine amides | JANSSEN PHARMACEUTICA NV (BE) | 2011-03-29 | — | — | US | disclosed |