Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 8/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.43 |
| ▸ | HPGD | P15428 | 6/20 | 0.43 |
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | CES1 | P23141 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 6/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | ERCC5 | P28715 | 3/20 | 0.40 |
| ▸ | FEN1 | P39748 | 3/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19665784 | 0.83 | PDK2 (0.42) | KMT2AHPGDMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL12251790 | 0.83 | PTPN1 (0.52) | HPGDMAPTKDM4EALOX15HTT | |
| SCHEMBL14564259 | 0.80 | HPGD (0.44) | MEN1KMT2AHPGDMAPTKDM4E | |
| SCHEMBL6038446 | 0.79 | ALDH1A1 (0.42) | MEN1KMT2AHPGDMAPTKDM4E | |
| SCHEMBL12894823 | 0.79 | CTSD (0.50) | MEN1KMT2AHPGDMAPTKDM4E | |
| SCHEMBL6053746 | 0.79 | SMN1; SMN2 (0.37) | MEN1KMT2AHPGDMAPTKDM4E | |
| SCHEMBL1081928 | 0.77 | ALDH1A1 (0.59) | MEN1KMT2AHPGDMAPTKDM4E | |
| SCHEMBL13612917 | 0.76 | F2R (0.33) | HPGDMAPTKDM4ELMNAALDH1A1 | |
| SCHEMBL14232815 | 0.76 | ALDH1A1 (0.39) | MEN1KMT2AHPGDMAPTKDM4E | |
| SCHEMBL840117 | 0.76 | ALDH1A1 (0.61) | MEN1KMT2AHPGDMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130053556-A1 | Photocleavable morpholino oligos with integral photolinkers for modulating the activity of any selected gene transcript by exposure to light | GENE TOOLS, LLC (US) | 2013-02-28 | — | — | US | disclosed |
| US-20130053556-A1 | Photocleavable morpholino oligos with integral photolinkers for modulating the activity of any selected gene transcript by exposure to light | GENE TOOLS, LLC (US) | 2013-02-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130053556-A1 | Photocleavable morpholino oligos with integral photolinkers for modulating the activity of any selected gene transcript by exposure to light | MITF, RTCB, UPF1 | MEN1 2739/4885KMT2A 980/4885HPGD 3974/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.