SCHEMBL14718249

SCHEMBL14718249

CCCCOc1c(C)ccc(C(C)(C)C)c1O

nearest known ligand 0.45

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
SCN2A Q99250 2/20 0.45
GABRA1 P14867 1/20 0.41
GABRB2 P47870 1/20 0.41
ALDH1A1 P00352 4/20 0.38
ESR1 P03372 2/20 0.38
LTA4H P09960 2/20 0.38
NR5A1 Q13285 1/20 0.38
CA2 P00918 1/20 0.37
GAA P10253 2/20 0.37
XBP1 P17861 1/20 0.35
ATM Q13315 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
KDM4E B2RXH2 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
HSPA5 P11021 1/20 0.34
PTGS1 P23219 2/20 0.34
PTGS2 P35354 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29712146 0.76 LTA4H (0.43) ALDH1A1LTA4HNR5A1CA2NPSR1
SCHEMBL21026776 0.72 THRA (0.46) ALDH1A1ESR1LTA4HNR5A1CA2
SCHEMBL12646952 0.72 ALDH1A1 (0.46) SCN2AGABRA1GABRB2ALDH1A1LTA4H
SCHEMBL5587446 0.72 LTA4H (0.40) ESR1LTA4HNR5A1KDM4ESMN1; SMN2
SCHEMBL27934690 0.72 ALDH1A1 (0.46) SCN2AALDH1A1LTA4HCA2GAA
SCHEMBL15187968 0.71 PDIA6 (0.46) ALDH1A1LTA4HNR5A1CA2GAA
SCHEMBL8297104 0.71 ALDH1A1 (0.44) ALDH1A1LTA4HNR5A1NPSR1KDM4E
SCHEMBL28974964 0.71 LTA4H (0.42) ESR1LTA4HNR5A1SMN1; SMN2
SCHEMBL862392 0.71 ALDH1A1 (0.46) ALDH1A1LTA4HNR5A1CA2NPSR1
SCHEMBL14594240 0.70 RXRA (0.47) SCN2AALDH1A1ESR1NR5A1NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130052573-A1 NOVEL REACTIVE COMPOUND, CHARGE TRANSPORTING FILM, PHOTOELECTRIC CONVERSION DEVICE, ELECTROPHOTOGRAPHIC PHOTORECEPTOR AND METHOD OF PRODUCING THE SAME, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS FUJI XEROX CO., LTD. (JP) 2013-02-28 US disclosed