SCHEMBL14719271

SCHEMBL14719271

Cc1cc(B2OC(C)(C)C(C)(C)O2)cn(C)c1=O

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 7/20 0.40
BRD9 Q9H8M2 3/20 0.38
CA1 P00915 2/20 0.36
CA2 P00918 2/20 0.36
CA9 Q16790 2/20 0.36
IDO1 P14902 1/20 0.36
TDO2 P48775 1/20 0.36
LPL P06858 5/20 0.35
LIPG Q9Y5X9 5/20 0.35
FFAR1 O14842 1/20 0.34
CA12 O43570 1/20 0.33
CA3 P07451 1/20 0.33
CA4 P22748 1/20 0.33
CA6 P23280 1/20 0.33
CA5A P35218 1/20 0.33
CA7 P43166 1/20 0.33
CA14 Q9ULX7 1/20 0.33
CA5B Q9Y2D0 1/20 0.33
F11 P03951 2/20 0.33
CSF1R P07333 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22325994 0.90 BRD4 (0.37) BRD4BRD9CA1CA2CA9
SCHEMBL29848701 0.89 BRD4 (0.34) BRD4BRD9CA1CA2CA9
SCHEMBL29948355 0.89 CA1 (0.34) BRD4BRD9CA1CA2CA9
SCHEMBL16651646 0.85 CA1 (0.36) BRD4CA1CA2CA9IDO1
SCHEMBL23001755 0.82 CA1 (0.36) CA1CA2CA9IDO1TDO2
SCHEMBL21224665 0.82 AURKA (0.40) BRD4CA1CA2CA9IDO1
SCHEMBL22339403 0.82 LPL (0.34) CA1CA2CA9IDO1TDO2
SCHEMBL16650516 0.82 LPL (0.40) CA1CA2CA9IDO1TDO2
SCHEMBL18496375 0.81 LIPG (0.38) CA1CA2CA9IDO1TDO2
SCHEMBL16650743 0.80 LPL (0.33) CA1CA2CA9IDO1TDO2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 221 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026107371-A2 INDOLYL-PYRIDINONES AND RELATED COMPOUNDS AND THEIR USE IN THERAPY HOTSPOT THERAPEUTICS, INC. (US) 2026-05-21 WO disclosed
US-20260098028-A1 Compounds and Their Use for Treatment of Hemoglobinopathies BRISTOL-MYERS SQUIBB COMPANY (US) 2026-04-09 US disclosed
US-12558341-B2 Oral complement factor D inhibitors BIOCRYST PHARMACEUTICALS, INC. (US) 2026-02-24 US disclosed
US-20260008778-A1 COMPOUNDS AND USES THEREOF FOGHORN THERAPEUTICS INC (US) 2026-01-08 US disclosed
EP-4674484-A2 THIENOPYRROLE COMPOUNDS Gilead Sciences, Inc. (US) 2026-01-07 EP disclosed
US-12497392-B2 EP300/CBP inhibitor HINOVA PHARMACEUTICALS INC. (CN) 2025-12-16 US disclosed
US-12497395-B2 Small molecule bromodomain inhibitors and uses therof CONVERGENE, LLC 2025-12-16 US disclosed
US-12441711-B2 Compounds and their use for treatment of hemoglobinopathies BRISTOL-MYERS SQUIBB COMPANY (US) 2025-10-14 US disclosed
EP-4291562-B1 THIENOPYRROLE COMPOUNDS GILEAD SCIENCES INC (US) 2025-09-10 EP disclosed
EP-4612128-A1 COMPOUNDS AND THEIR USE FOR TREATMENT OF HEMOGLOBINOPATHIES Bristol-Myers Squibb Company (US) 2025-09-10 EP disclosed
US-20140288048-A1 HETEROCYCLIC COMPOUNDS AND USES THEREOF INFINITY PHARMACEUTICALS, INC. 2014-09-25 US disclosed
US-20140288048-A1 HETEROCYCLIC COMPOUNDS AND USES THEREOF INFINITY PHARMACEUTICALS, INC. 2014-09-25 US disclosed
US-8785470-B2 Heterocyclic compounds and uses thereof INFINITY PHARMACEUTICALS, INC. (US) 2014-07-22 US disclosed
US-8785470-B2 Heterocyclic compounds and uses thereof INFINITY PHARMACEUTICALS, INC. (US) 2014-07-22 US disclosed
EP-2751093-A1 HETEROCYCLIC COMPOUNDS AND USES THEREOF Infinity Pharmaceuticals, Inc. (US) 2014-07-09 EP disclosed
US-20140100214-A1 HETEROCYCLIC COMPOUNDS AND USES THEREOF INFINITY PHARMACEUTICALS, INC. (US) 2014-04-10 US disclosed
WO-2013032591-A1 HETEROCYCLIC COMPOUNDS AND USES THEREOF INFINITY PHARMACEUTICALS INC. (US) 2013-03-07 WO disclosed
WO-2013032591-A1 HETEROCYCLIC COMPOUNDS AND USES THEREOF INFINITY PHARMACEUTICALS INC. (US) 2013-03-07 WO disclosed
US-20130053362-A1 HETEROCYCLIC COMPOUNDS AND USES THEREOF INTELLKINE, LLC (US) 2013-02-28 US disclosed
US-20130053362-A1 HETEROCYCLIC COMPOUNDS AND USES THEREOF INTELLKINE, LLC (US) 2013-02-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140288048-A1 HETEROCYCLIC COMPOUNDS AND USES THEREOF AKT3, PIK3CA, AKT1 BRD4 1018/4885BRD9 1767/4885CA1 2993/4885
US-20130053362-A1 HETEROCYCLIC COMPOUNDS AND USES THEREOF AKT3, PIK3CA, AKT1 BRD4 1018/4885BRD9 1767/4885CA1 2993/4885
US-12497392-B2 EP300/CBP inhibitor EP300, MLLT1, CREBBP BRD4 11/4885BRD9 17/4885CA1 2938/4885
US-20140100214-A1 HETEROCYCLIC COMPOUNDS AND USES THEREOF AKT3, PIK3CA, AKT1 BRD4 1018/4885BRD9 1767/4885CA1 2993/4885
US-12497395-B2 Small molecule bromodomain inhibitors and uses therof BRD4, BRPF3, BICRA BRD4 1/4885BRD9 18/4885CA1 4765/4885
US-12558341-B2 Oral complement factor D inhibitors CFD, CFH, CFB BRD4 3880/4885BRD9 1393/4885CA1 3369/4885
US-12441711-B2 Compounds and their use for treatment of hemoglobinopathies HBG1, HBG2, HBB BRD4 3763/4885BRD9 3992/4885CA1 4815/4885
US-20260098028-A1 Compounds and Their Use for Treatment of Hemoglobinopathies HBZ, HBG2, HBB BRD4 4085/4885BRD9 3066/4885CA1 2066/4885
US-20260008778-A1 COMPOUNDS AND USES THEREOF BRD9, BCL9L, BCL9 BRD4 127/4885BRD9 1/4885CA1 3761/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.