Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FASN | P49327 | 1/20 | 0.43 |
| ▸ | LIMK2 | P53671 | 2/20 | 0.38 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.35 |
| ▸ | EED | O75530 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14720250 | 0.88 | FASN (0.53) | FASNKMT2A | |
| SCHEMBL14720297 | 0.85 | LIMK2 (0.48) | FASNLIMK2TPSAB1KMT2AMEN1 | |
| SCHEMBL22858909 | 0.76 | NPC1 (0.41) | KMT2AUTS2RNPC1RAB9AEED | |
| SCHEMBL22858905 | 0.76 | NPC1 (0.41) | KMT2AUTS2RNPC1RAB9AEED | |
| Hydrochloric Acid SCHEMBL14721951 | 0.75 | USP30 (0.45) | KMT2AMEN1 | |
| SCHEMBL14720344 | 0.74 | OPRM1 (0.42) | ALDH1A1KDM4E | |
| SCHEMBL14720096 | 0.73 | OXTR (0.32) | KMT2AUTS2REEDKDM4EOXTR | |
| SCHEMBL22220786 | 0.73 | FASN (0.58) | FASNOXTRAVPR1A | |
| SCHEMBL14720668 | 0.73 | OPRD1 (0.39) | LIMK2TPSAB1KMT2AITGB3ITGA2B | |
| SCHEMBL22220858 | 0.72 | FASN (0.56) | FASNKMT2AMEN1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013028445-A1 | FATTY ACID SYNTHASE INHIBITORS | GLAXOSMITHKLINE LLC (US) | 2013-02-28 | — | — | WO | disclosed |