Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | PDE6D | O43924 | 1/20 | 0.37 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 2/20 | 0.37 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.37 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14720297 | 0.84 | LIMK2 (0.48) | OPRD1LIMK2CHRM2CHRM3TPSAB1 | |
| SCHEMBL14720344 | 0.82 | OPRM1 (0.42) | OPRD1 | |
| SCHEMBL14720201 | 0.78 | HDAC1 (0.52) | CHRM2CHRM3KMT2A | |
| SCHEMBL14731371 | 0.78 | SMN1; SMN2 (0.46) | L3MBTL1SMN1; SMN2POLBKMT2A | |
| SCHEMBL14720407 | 0.74 | CHRM3 (0.39) | OPRD1HRH3CHRM2CHRM3POLB | |
| SCHEMBL14731339 | 0.73 | MCHR1 (0.49) | CHRM2SMN1; SMN2POLBGPR119 | |
| SCHEMBL14720449 | 0.73 | CHRM3 (0.52) | CHRM2CHRM3KMT2A | |
| SCHEMBL14720115 | 0.73 | FASN (0.43) | LIMK2TPSAB1ITGB3ITGA2BKMT2A | |
| SCHEMBL14720130 | 0.72 | CHIT1 (0.52) | TPSAB1KMT2ANAMPT | |
| SCHEMBL29134282 | 0.71 | DPP8 (0.36) | HRH3SMN1; SMN2POLBKMT2ADPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013028445-A1 | FATTY ACID SYNTHASE INHIBITORS | GLAXOSMITHKLINE LLC (US) | 2013-02-28 | — | — | WO | disclosed |