Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | FPR2 | P25090 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | GRK2 | P25098 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14720195 | 0.83 | USP30 (0.55) | HDAC2ALDH1A1L3MBTL1TDP1MAPT | |
| SCHEMBL2298548 | 0.77 | KIT (0.43) | HDAC2ALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2297057 | 0.76 | USP30 (0.50) | HDAC2ALDH1A1L3MBTL1TDP1MAPT | |
| SCHEMBL14720397 | 0.75 | THRB (0.58) | ALDH1A1L3MBTL1TDP1MAPTGAA | |
| SCHEMBL2300230 | 0.72 | HDAC2 (0.39) | HDAC2ALDH1A1RAB9APOLBKDM4E | |
| SCHEMBL31417758 | 0.72 | USP30 (0.61) | HDAC2ALDH1A1L3MBTL1TDP1MAPT | |
| SCHEMBL2298365 | 0.71 | THRB (0.44) | ALDH1A1MAPTGAATHRBAAK1 | |
| SCHEMBL14342873 | 0.70 | GPR183 (0.44) | ALDH1A1THRBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL1119389 | 0.68 | CASP6 (0.60) | ALDH1A1L3MBTL1TDP1MAPTGAA | |
| SCHEMBL15874474 | 0.68 | THRB (0.52) | ALDH1A1MAPTTHRBAAK1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013028445-A1 | FATTY ACID SYNTHASE INHIBITORS | GLAXOSMITHKLINE LLC (US) | 2013-02-28 | — | — | WO | disclosed |