Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | PTGIR | P43119 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14720757 | 0.86 | CHRM3 (0.44) | LMNACHRM3HDAC8PTGIR | |
| SCHEMBL14720616 | 0.80 | LIMK2 (0.36) | CNR1CNR2 | |
| SCHEMBL14720171 | 0.77 | CNR1 (0.33) | LMNACHRM3CNR1CNR2 | |
| SCHEMBL14720407 | 0.74 | CHRM3 (0.39) | LMNACHRM3PTGIR | |
| SCHEMBL14720417 | 0.71 | HDAC3 (0.41) | LMNAHDAC8 | |
| SCHEMBL14720215 | 0.70 | GRIN2B (0.44) | LMNACHRM3 | |
| SCHEMBL14720555 | 0.67 | FASN (0.37) | — | |
| SCHEMBL14720167 | 0.65 | CYP3A4 (0.46) | LMNA | |
| SCHEMBL20549605 | 0.64 | RAB9A (0.42) | LMNA | |
| SCHEMBL14720415 | 0.64 | DRD2 (0.38) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013028445-A1 | FATTY ACID SYNTHASE INHIBITORS | GLAXOSMITHKLINE LLC (US) | 2013-02-28 | — | — | WO | disclosed |