Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.41 |
| ▸ | L3MBTL3 | Q96JM7 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14720575 | 0.85 | L3MBTL3 (0.51) | HRH3L3MBTL3L3MBTL1MBTD1KMT2A | |
| SCHEMBL14720710 | 0.82 | HRH3 (0.56) | HRH3L3MBTL3L3MBTL1SMN1; SMN2 | |
| SCHEMBL14720524 | 0.81 | PDE4A (0.35) | L3MBTL1SMN1; SMN2 | |
| SCHEMBL14720525 | 0.81 | PDE4A (0.35) | L3MBTL1SMN1; SMN2 | |
| SCHEMBL14720597 | 0.80 | POLB (0.38) | HRH3KMT2A | |
| SCHEMBL14721065 | 0.80 | HRH3 (0.41) | HRH3L3MBTL3L3MBTL1MBTD1KMT2A | |
| SCHEMBL14731055 | 0.80 | HRH3 (0.53) | HRH3L3MBTL3L3MBTL1SMN1; SMN2KMT2A | |
| SCHEMBL14731088 | 0.79 | HRH3 (0.38) | HRH3L3MBTL3L3MBTL1KMT2A | |
| SCHEMBL14720875 | 0.78 | FKBP1A (0.38) | HRH3 | |
| SCHEMBL14720876 | 0.78 | FKBP1A (0.38) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013027001-A1 | COMPOUNDS AND THEIR USE TO TREAT HISTAMINE H3 RELATED DISORDERS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2013-02-28 | — | — | WO | claimed |
| WO-2013027001-A1 | COMPOUNDS AND THEIR USE TO TREAT HISTAMINE H3 RELATED DISORDERS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2013-02-28 | — | — | WO | disclosed |
| WO-2013027001-A1 | COMPOUNDS AND THEIR USE TO TREAT HISTAMINE H3 RELATED DISORDERS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2013-02-28 | — | — | WO | disclosed |